caa a22 4500 60618693X CHVBK 20210128100838.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s00405-013-2862-9 doi (NATIONALLICENCE)springer-10.1007/s00405-013-2862-9 Lower cranial nerves function after surgical treatment of Fisch Class C and D tympanojugular paragangliomas [Elektronische Daten] [Andrea Bacciu, Marimar Medina, Hassen Ait Mimoune, Flavia D'Orazio, Enrico Pasanisi, Giorgio Peretti, Mario Sanna] The aim of this study was to report the postoperative lower cranial nerves (LCNs) function in patients undergoing surgery for tympanojugular paraganglioma (TJP) and to evaluate risk factors for postoperative LCN dysfunction. A retrospective case review of 122 patients having Fisch class C or D TJP, surgically treated from 1988 to 2012, was performed. The follow-up of the series ranged from 12 to 156months (mean, 39.4±32.6months). The infratemporal type A approach was the most common surgical procedure. Gross total tumor removal was achieved in 86% of cases. Seventy-two percent of the 54 patients with preoperative LCN deficit had intracranial tumor extension. Intraoperatively, LCNs had to be sacrificed in 63 cases (51.6%) due to tumor infiltration. Sixty-six patients (54.09%) developed a new deficit of one or more of the LCNs. Of those patients who developed new LCN deficits, 23 of them had intradural extension. Postoperative follow-up of at least 1year showed that the LCN most commonly affected was the CN IX (50%). Logistic regression analysis showed that intracranial transdural tumor extension was correlated with the higher risk of LCN sacrifice (p<0.05). Despite the advances in skull base surgery, new postoperative LCN deficits still represent a challenge. The morbidity associated with resection of the LCNs is dependent on the tumor's size and intradural tumor extension. Though no recovery of LCN deficits may be expected, on long-term follow-up, patients usually compensate well for their LCNs loss. Springer-Verlag Berlin Heidelberg, 2013 Tympanojugular paraganglioma nationallicence Glomus tumor nationallicence Lower cranial nerve outcomes nationallicence Intradural extension nationallicence Lower cranial nerve palsy nationallicence Paraganglioma nationallicence Bacciu Andrea Otolaryngology Unit, Department of Experimental and Clinical Medicine, University-Hospital of Parma, Parma, Italy aut Medina Marimar Gruppo Otologico, Via Emmanueli, 42, 29121, Piacenza, Italy aut Ait Mimoune Hassen Gruppo Otologico, Via Emmanueli, 42, 29121, Piacenza, Italy aut D'Orazio Flavia Gruppo Otologico, Via Emmanueli, 42, 29121, Piacenza, Italy aut Pasanisi Enrico Otolaryngology Unit, Department of Experimental and Clinical Medicine, University-Hospital of Parma, Parma, Italy aut Peretti Giorgio Department of Otolaryngology Head Neck Surgery, University of Genova, Genova, Italy aut Sanna Mario Gruppo Otologico, Via Emmanueli, 42, 29121, Piacenza, Italy aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/2(2015-02-01), 311-319 0937-4477 272:2<311 2015 272 405 https://doi.org/10.1007/s00405-013-2862-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-013-2862-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bacciu Andrea Otolaryngology Unit, Department of Experimental and Clinical Medicine, University-Hospital of Parma, Parma, Italy aut NATIONALLICENCE 700 1- Medina Marimar Gruppo Otologico, Via Emmanueli, 42, 29121, Piacenza, Italy aut NATIONALLICENCE 700 1- Ait Mimoune Hassen Gruppo Otologico, Via Emmanueli, 42, 29121, Piacenza, Italy aut NATIONALLICENCE 700 1- D'Orazio Flavia Gruppo Otologico, Via Emmanueli, 42, 29121, Piacenza, Italy aut NATIONALLICENCE 700 1- Pasanisi Enrico Otolaryngology Unit, Department of Experimental and Clinical Medicine, University-Hospital of Parma, Parma, Italy aut NATIONALLICENCE 700 1- Peretti Giorgio Department of Otolaryngology Head Neck Surgery, University of Genova, Genova, Italy aut NATIONALLICENCE 700 1- Sanna Mario Gruppo Otologico, Via Emmanueli, 42, 29121, Piacenza, Italy aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/2(2015-02-01), 311-319 0937-4477 272:2<311 2015 272 405