caa a22 4500 606186980 CHVBK 20210128100838.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s00405-014-3119-y doi (NATIONALLICENCE)springer-10.1007/s00405-014-3119-y Surgical management of recurrent sinonasal mucosal melanoma: endoscopic or transfacial resection [Elektronische Daten] [G. Ledderose, A. Leunig] Sinonasal mucosal melanoma (SNMM) is associated with poor prognosis. Local recurrence is common and represents a major problem in the therapy. Wide resection surgery is usually applied. However, given the almost futile prognosis, optimal symptom control may be preferable to wide resection at all costs. The aim of our study was to analyze the outcome in patients with recurrent SNMM treated by transfacial radical surgery or by a less invasive endoscopically controlled approach. Patients with recurrent grade III or IV staged SNMM who presented to our ENT department between 2000 and 2010 were either treated by transfacial (n=10) or endoscopically controlled surgery (n=12). The patients' charts were reviewed for clinical symptoms, relapse-free time and survival time. Clinical symptoms improved after surgery. The morbidity after endoscopic surgery was significantly lower than after transfacial surgery. The chosen surgical technique did neither affect relapse-free nor survival time. When treating recurrent SNMM, the comparatively gentle and less mutilating endoscopic approach proved to be a sufficient surgical procedure, being not inferior to aggressive surgery with respect to recurrence and survival rate. Springer-Verlag Berlin Heidelberg, 2014 Sinonasal mucosal melanoma nationallicence SNMM nationallicence Local recurrence nationallicence Survival nationallicence Relapse-free time nationallicence Endonasal nationallicence Extranasal nationallicence Ledderose G. Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilian University Munich, Marchioninistr. 15, 81377, Munich, Germany aut Leunig A. Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilian University Munich, Marchioninistr. 15, 81377, Munich, Germany aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/2(2015-02-01), 351-356 0937-4477 272:2<351 2015 272 405 https://doi.org/10.1007/s00405-014-3119-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3119-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ledderose G. Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilian University Munich, Marchioninistr. 15, 81377, Munich, Germany aut NATIONALLICENCE 700 1- Leunig A. Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilian University Munich, Marchioninistr. 15, 81377, Munich, Germany aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/2(2015-02-01), 351-356 0937-4477 272:2<351 2015 272 405