caa a22 4500 606187170 CHVBK 20210128100839.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00405-014-3370-2 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3370-2 Health-related quality of life measurement after cholesteatoma surgery: comparison of three different surgical techniques [Elektronische Daten] [Susen Lailach, Max Kemper, Nikoloz Lasurashvili, Thomas Beleites, Thomas Zahnert, Marcus Neudert] The objective of this study was to compare health-related quality of life (HRQOL) after sequential cholesteatoma surgery including exclusively transcanal technique (ETC), combined transcanal transmastoidal technique (TCM) and canal wall down surgery with obliteration (CWD). It was a clinical case study conducted in a tertiary referral center. 97 patients at least 12months after cholesteatoma surgery were included. Interventions included sequential cholesteatoma surgery with ETC, TCM or CWD; ossiculoplasty with partial and total ossicular replacement prostheses. HRQOL assessed by Chronic Otitis Media Outcome Test 15 including an overall score and three subscores (‘ear symptoms', ‘hearing function' and ‘mental health') as well as a general evaluation of HRQOL and the frequency of physician consultations, audiometric outcome related to HRQOL were the main outcome measures. Patients, who had undergone sequential cholesteatoma surgery, showed moderate restrictions in HRQOL postoperatively. Stratified for the three surgical techniques, patients receiving ETC tended to report lower restrictions in HRQOL. The ETC group offered a significantly lower value in the subscore ‘ear symptoms'. The ‘hearing function' was attributed to be the most restriction criteria for all techniques. The overall score and all subscores correlated moderately with the postoperative air conduction threshold. The strongest correlation coefficient was achieved for the subscore ‘hearing function' (r s=0.49, p<0.001). Sequential cholesteatoma surgery offers acceptable moderate restrictions in HRQOL postoperatively. Patients receiving canal wall down surgery with obliteration showed equivalent limitations in HRQOL compared to closed techniques (ETC, TCM). The postoperative air conduction threshold was shown not to be a sufficient indicator for HRQOL. Therefore, disease-specific validated and reliable measuring instruments for HRQOL should be transferred from clinical research to clinical practice to provide an individualized postoperative assessment after cholesteatoma surgery. Springer-Verlag Berlin Heidelberg, 2014 Health-related quality of life nationallicence Cholesteatoma nationallicence Surgical technique nationallicence Intact canal wall nationallicence Canal wall down nationallicence Lailach Susen Department of Otorhinolaryngology, Head and Neck Surgery, Technische Universität Dresden, Medizinische Fakultät Carl Gustav Carus, Fetscher Strasse 74, 01307, Dresden, Saxony, Germany aut Kemper Max Department of Otorhinolaryngology, Head and Neck Surgery, Technische Universität Dresden, Medizinische Fakultät Carl Gustav Carus, Fetscher Strasse 74, 01307, Dresden, Saxony, Germany aut Lasurashvili Nikoloz Department of Otorhinolaryngology, Head and Neck Surgery, Technische Universität Dresden, Medizinische Fakultät Carl Gustav Carus, Fetscher Strasse 74, 01307, Dresden, Saxony, Germany aut Beleites Thomas Department of Otorhinolaryngology, Head and Neck Surgery, Technische Universität Dresden, Medizinische Fakultät Carl Gustav Carus, Fetscher Strasse 74, 01307, Dresden, Saxony, Germany aut Zahnert Thomas Department of Otorhinolaryngology, Head and Neck Surgery, Technische Universität Dresden, Medizinische Fakultät Carl Gustav Carus, Fetscher Strasse 74, 01307, Dresden, Saxony, Germany aut Neudert Marcus Department of Otorhinolaryngology, Head and Neck Surgery, Technische Universität Dresden, Medizinische Fakultät Carl Gustav Carus, Fetscher Strasse 74, 01307, Dresden, Saxony, Germany aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/11(2015-11-01), 3177-3185 0937-4477 272:11<3177 2015 272 405 https://doi.org/10.1007/s00405-014-3370-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3370-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lailach Susen Department of Otorhinolaryngology, Head and Neck Surgery, Technische Universität Dresden, Medizinische Fakultät Carl Gustav Carus, Fetscher Strasse 74, 01307, Dresden, Saxony, Germany aut NATIONALLICENCE 700 1- Kemper Max Department of Otorhinolaryngology, Head and Neck Surgery, Technische Universität Dresden, Medizinische Fakultät Carl Gustav Carus, Fetscher Strasse 74, 01307, Dresden, Saxony, Germany aut NATIONALLICENCE 700 1- Lasurashvili Nikoloz Department of Otorhinolaryngology, Head and Neck Surgery, Technische Universität Dresden, Medizinische Fakultät Carl Gustav Carus, Fetscher Strasse 74, 01307, Dresden, Saxony, Germany aut NATIONALLICENCE 700 1- Beleites Thomas Department of Otorhinolaryngology, Head and Neck Surgery, Technische Universität Dresden, Medizinische Fakultät Carl Gustav Carus, Fetscher Strasse 74, 01307, Dresden, Saxony, Germany aut NATIONALLICENCE 700 1- Zahnert Thomas Department of Otorhinolaryngology, Head and Neck Surgery, Technische Universität Dresden, Medizinische Fakultät Carl Gustav Carus, Fetscher Strasse 74, 01307, Dresden, Saxony, Germany aut NATIONALLICENCE 700 1- Neudert Marcus Department of Otorhinolaryngology, Head and Neck Surgery, Technische Universität Dresden, Medizinische Fakultät Carl Gustav Carus, Fetscher Strasse 74, 01307, Dresden, Saxony, Germany aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/11(2015-11-01), 3177-3185 0937-4477 272:11<3177 2015 272 405