caa a22 4500 606187243 CHVBK 20210128100839.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00405-014-3437-0 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3437-0 Cross-cultural adaptation and validation of the sino-nasal outcome test (SNOT-22) for Spanish-speaking patients [Elektronische Daten] [Gonzalo de los Santos, Pablo Reyes, Raúl del Castillo, Claudio Fragola, Ana Royuela] Our objective was to perform translation, cross-cultural adaptation and validation of the sino-nasal outcome test 22 (SNOT-22) to Spanish language. SNOT-22 was translated, back translated, and a pretest trial was performed. The study included 119 individuals divided into 60 cases, who met diagnostic criteria for chronic rhinosinusitis according to the European Position Paper on Rhinosinusitis 2012; and 59 controls, who reported no sino-nasal disease. Internal consistency was evaluated with Cronbach's alpha test, reproducibility with Kappa coefficient, reliability with intraclass correlation coefficient (ICC), validity with Mann-Whitney U test and responsiveness with Wilcoxon test. In cases, Cronbach's alpha was 0.91 both before and after treatment, as for controls, it was 0.90 at their first test assessment and 0.88 at 3weeks. Kappa coefficient was calculated for each item, with an average score of 0.69. ICC was also performed for each item, with a score of 0.87 in the overall score and an average among all items of 0.71. Median score for cases was 47, and 2 for controls, finding the difference to be highly significant (Mann-Whitney U test, p<0.001). Clinical changes were observed among treated patients, with a median score of 47 and 13.5 before and after treatment, respectively (Wilcoxon test, p<0.001). The effect size resulted in 0.14 in treated patients whose status at 3weeks was unvarying; 1.03 in those who were better and 1.89 for much better group. All controls were unvarying with an effect size of 0.05. The Spanish version of the SNOT-22 has the internal consistency, reliability, reproducibility, validity and responsiveness necessary to be a valid instrument to be used in clinical practice. Springer-Verlag Berlin Heidelberg, 2014 Chronic rhinosinusitis nationallicence Sino-nasal outcome test 22 nationallicence SNOT-22 nationallicence Spanish language nationallicence Nasal polyposis nationallicence Quality of life nationallicence de los Santos Gonzalo Department of Otorhinolaryngology, Ramon y Cajal University Hospital, Ctra. Colmenar Viejo Km 9, 100, 28034, Madrid, Spain aut Reyes Pablo Department of Otorhinolaryngology, Ramon y Cajal University Hospital, Ctra. Colmenar Viejo Km 9, 100, 28034, Madrid, Spain aut del Castillo Raúl Department of Otorhinolaryngology, Ramon y Cajal University Hospital, Ctra. Colmenar Viejo Km 9, 100, 28034, Madrid, Spain aut Fragola Claudio Department of Otorhinolaryngology, Ramon y Cajal University Hospital, Ctra. Colmenar Viejo Km 9, 100, 28034, Madrid, Spain aut Royuela Ana CIBER, Epidemiología y Salud Pública, Clinical Biostatistics Unit, Ramon y Cajal University Hospital, IRYCIS, Ctra. Colmenar Viejo Km 9, 100, 28034, Madrid, Spain aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/11(2015-11-01), 3335-3340 0937-4477 272:11<3335 2015 272 405 https://doi.org/10.1007/s00405-014-3437-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3437-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- de los Santos Gonzalo Department of Otorhinolaryngology, Ramon y Cajal University Hospital, Ctra. Colmenar Viejo Km 9, 100, 28034, Madrid, Spain aut NATIONALLICENCE 700 1- Reyes Pablo Department of Otorhinolaryngology, Ramon y Cajal University Hospital, Ctra. Colmenar Viejo Km 9, 100, 28034, Madrid, Spain aut NATIONALLICENCE 700 1- del Castillo Raúl Department of Otorhinolaryngology, Ramon y Cajal University Hospital, Ctra. Colmenar Viejo Km 9, 100, 28034, Madrid, Spain aut NATIONALLICENCE 700 1- Fragola Claudio Department of Otorhinolaryngology, Ramon y Cajal University Hospital, Ctra. Colmenar Viejo Km 9, 100, 28034, Madrid, Spain aut NATIONALLICENCE 700 1- Royuela Ana CIBER, Epidemiología y Salud Pública, Clinical Biostatistics Unit, Ramon y Cajal University Hospital, IRYCIS, Ctra. Colmenar Viejo Km 9, 100, 28034, Madrid, Spain aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/11(2015-11-01), 3335-3340 0937-4477 272:11<3335 2015 272 405