caa a22 4500 606187286 CHVBK 20210128100840.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00405-015-3657-y doi (NATIONALLICENCE)springer-10.1007/s00405-015-3657-y The effect of antireflux surgery on laryngeal symptoms, findings and voice parameters [Elektronische Daten] [Mustafa Sahin, Rukiye Vardar, Sinan Ersin, Tayfun Kirazli, M. Ogut, N. Akyildiz, Serhat Bor] The aim of this study was to evaluate the effect of laparoscopic antireflux surgery (LARS) on the laryngeal symptoms, physical findings and voice parameters of gastroesophageal reflux disease (GERD) patients with or without laryngopharyngeal reflux (LPR). Forty-one GERD patients predominantly with LPR symptoms (Group I) and twenty-six GERD patients without LPR symptoms (Group II) who had LARS were prospectively analysed before and 2years after the surgery. Upper gastrointestinal endoscopy, 24-h ambulatory pH or MII-pH monitoring was performed in all cases. A reflux study group including specialists from five departments in a university hospital decided surgical indications. Patients were asked to fill out a validated LPR and voice quality questionnaire (Reflux Symptom Index and Voice Handicap Index-10). Laryngeal findings were evaluated and scored using a laryngoscopic grading scale [Reflux Finding Score (RFS)], by four blinded ENT specialists. GRBAS scale was done by a blinded otolaryngologist. Voice parameters were measured objectively via the Multi Dimensional Voice Programme (MDVP). The mean age was 45.8±8.5 for Group I (24 men) and 48.9±12.3 for Group II (16 men). The mean follow-up after LARS was 24.5±1.3months for Group I and 25.2±1.1months for Group II. The preoperative mean score of RSI was 22.8±7.4 vs. 11.2±6.6; RFS was 10.6±2.3 vs. 5.7±2.5 and VHI was 18.07±4.4 vs. 10.86±3.3 for Group I and II, respectively. The postoperative mean score of RSI was 12.9±6.4 vs. 8.4±4.5; RFS was 6.9±2.0 vs. 4.5±2.3 and VHI was 9.59±4.4 vs. 7.95±3.5 for Group I and II, respectively. Group I had significantly lower RSI and RFS scores following LARS compared to the preoperative scores. LARS successfully improved RFS, RSI and VHI in carefully selected patients with GERD, especially the signs and symptoms related to the larynx and voice. Although the indications for LARS are limited in patients with LPR symptoms, these results favor the decision-making period of LARS. Springer-Verlag Berlin Heidelberg, 2015 Laryngopharyngeal reflux nationallicence Gastroesophageal reflux nationallicence Nissen fundoplication nationallicence Voice nationallicence Sahin Mustafa Department of Otorhinolaryngology, Adnan Menderes University Faculty of Medicine, 09100, Aydin, Turkey aut Vardar Rukiye Department of Gastroenterology, Ege University Faculty of Medicine, Izmir, Turkey aut Ersin Sinan Department of General Surgey, Ege University Faculty of Medicine, Izmir, Turkey aut Kirazli Tayfun Department of Otorhinolaryngology, Ege University Faculty of Medicine, Izmir, Turkey aut Ogut M. Department of Otorhinolaryngology, Ege University Faculty of Medicine, Izmir, Turkey aut Akyildiz N. Department of Otorhinolaryngology, Ege University Faculty of Medicine, Izmir, Turkey aut Bor Serhat Department of Gastroenterology, Ege University Faculty of Medicine, Izmir, Turkey aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/11(2015-11-01), 3375-3383 0937-4477 272:11<3375 2015 272 405 https://doi.org/10.1007/s00405-015-3657-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-015-3657-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sahin Mustafa Department of Otorhinolaryngology, Adnan Menderes University Faculty of Medicine, 09100, Aydin, Turkey aut NATIONALLICENCE 700 1- Vardar Rukiye Department of Gastroenterology, Ege University Faculty of Medicine, Izmir, Turkey aut NATIONALLICENCE 700 1- Ersin Sinan Department of General Surgey, Ege University Faculty of Medicine, Izmir, Turkey aut NATIONALLICENCE 700 1- Kirazli Tayfun Department of Otorhinolaryngology, Ege University Faculty of Medicine, Izmir, Turkey aut NATIONALLICENCE 700 1- Ogut M. Department of Otorhinolaryngology, Ege University Faculty of Medicine, Izmir, Turkey aut NATIONALLICENCE 700 1- Akyildiz N. Department of Otorhinolaryngology, Ege University Faculty of Medicine, Izmir, Turkey aut NATIONALLICENCE 700 1- Bor Serhat Department of Gastroenterology, Ege University Faculty of Medicine, Izmir, Turkey aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/11(2015-11-01), 3375-3383 0937-4477 272:11<3375 2015 272 405