caa a22 4500 606187413 CHVBK 20210128100840.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00405-014-3355-1 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3355-1 Xenogeneic acellular dermal matrix in combination with pectoralis major myocutaneous flap reconstructs hypopharynx and cervical esophagus [Elektronische Daten] [Danhui Yin, Qinglai Tang, Shuang Wang, Shisheng Li, Xiangbo He, Jiajia Liu, Bingbing Liu, Mi Yang, Xinming Yang] The aim of this study was to explore xenogeneic acellular dermal matrix (ADM) in combination with pectoralis major myocutaneous flap in hypopharynx and cervical esophagus reconstruction. A total of five patients were treated with this surgical method to reconstruct hypopharynx and cervical esophagus in Second Xiangya Hospital between January 2012 and April 2013. Four of them had hypopharyngeal carcinoma with laryngeal and cervical esophageal invasion, while the fifth patient with hypopharyngeal cancer had developed scars and atresia after postoperative radiotherapy. The defect length after hypopharyngeal and cervical esophageal resection was 6-8cm, and was repaired by a combination of ADM and pectoralis major myocutaneous flap by our team. Interestingly, the four patients had primary healing and regained their eating function about 2-3weeks after surgery, the fifth individual suffered from pharyngeal fistula, but recovered after dressing change about 2months. Postoperative esophageal barium meals revealed that the pharynx and esophagus were unobstructed in all five patients. Xenogeneic ADM in combination with pectoralis major myocutaneous flap for hypopharynx and cervical esophagus reconstruction is a simple, safe and effective method with fewer complications. Nevertheless, according to the defect length of the cervical esophagus, the patients need to strictly follow the medical advice. Springer-Verlag Berlin Heidelberg, 2014 Xenogeneic ADM nationallicence Pectoralis major myocutaneous flap nationallicence Hypopharyngeal carcinoma nationallicence Cervical esophagus nationallicence Yin Danhui Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut Tang Qinglai Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut Wang Shuang Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut Li Shisheng Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut He Xiangbo Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut Liu Jiajia Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut Liu Bingbing Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut Yang Mi Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut Yang Xinming Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/11(2015-11-01), 3457-3461 0937-4477 272:11<3457 2015 272 405 https://doi.org/10.1007/s00405-014-3355-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3355-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yin Danhui Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut NATIONALLICENCE 700 1- Tang Qinglai Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut NATIONALLICENCE 700 1- Wang Shuang Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut NATIONALLICENCE 700 1- Li Shisheng Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut NATIONALLICENCE 700 1- He Xiangbo Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut NATIONALLICENCE 700 1- Liu Jiajia Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut NATIONALLICENCE 700 1- Liu Bingbing Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut NATIONALLICENCE 700 1- Yang Mi Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut NATIONALLICENCE 700 1- Yang Xinming Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, People's Republic of China aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/11(2015-11-01), 3457-3461 0937-4477 272:11<3457 2015 272 405