caa a22 4500 606187456 CHVBK 20210128100840.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00405-014-3311-0 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3311-0 Predicting the outcome of modified tongue base suspension combined with uvulopalatopharyngoplasty [Elektronische Daten] [Murat Turhan, Asli Bostanci, Selen Bozkurt] The purpose of this study was to investigate the relationship between various polysomnographic variables and the success of modified tongue base suspension combined with uvulopharyngopalatoplasty in patients with severe obstructive sleep apnea (OSA). A total of 90 patients who had apnea hypopnea index (AHI) >30 and had both oropharyngeal and hypopharyngeal obstruction were included in this prospective case series with planned data collection. All patients were assessed preoperatively and at the sixth postoperative month by polysomnography. The surgery was considered to be successful when a ≥50% reduction in the mean AHI to a final AHI of <20/h was obtained. Multiple logistic regression analyses were performed to determine the impact of variables on the surgical success. A total of 67 patients (74.4%) met the surgical success criteria. The univariate analysis revealed a relationship between success and AHI (P=0.001), obstructive apnea duration (P=0.001), sleep time with oxygen saturation below 90% (ST90) (P=0.004), minimum O2 saturation (P=0.0001), mean O2 saturation (P=0.011), mean O2 desaturation (P=0.0001), and oxygen desaturation index (P=0.001). However, ST90 [OR (95% CI)=1.40 (1.04-1.89), P=0.023] was the only independent parameter predicting the surgical success in multivariate analysis. The ROC analysis revealed that the ST90 value of ≤36min was the best cutoff value with 96.97% sensitivity (CI 89.5-99.6), 95.83% specificity (CI 78.9-99.9), 98.5% PPV (CI 91.6-100.0), and 92.0% NPV (CI 74.0-99.0). The stratification of patients with severe OSA according to the ST90 may allow better identification of patients in whom surgical success is probable. Springer-Verlag Berlin Heidelberg, 2014 OSA nationallicence Surgical success nationallicence ST90 nationallicence Turhan Murat Department of Otolaryngology, Head and Neck Surgery, Akdeniz University School of Medicine, Antalya, Turkey aut Bostanci Asli Department of Otolaryngology, Head and Neck Surgery, Akdeniz University School of Medicine, Antalya, Turkey aut Bozkurt Selen Department of Biostatistics and Medical Informatics, Akdeniz University School of Medicine, Antalya, Turkey aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/11(2015-11-01), 3411-3416 0937-4477 272:11<3411 2015 272 405 https://doi.org/10.1007/s00405-014-3311-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3311-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Turhan Murat Department of Otolaryngology, Head and Neck Surgery, Akdeniz University School of Medicine, Antalya, Turkey aut NATIONALLICENCE 700 1- Bostanci Asli Department of Otolaryngology, Head and Neck Surgery, Akdeniz University School of Medicine, Antalya, Turkey aut NATIONALLICENCE 700 1- Bozkurt Selen Department of Biostatistics and Medical Informatics, Akdeniz University School of Medicine, Antalya, Turkey aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/11(2015-11-01), 3411-3416 0937-4477 272:11<3411 2015 272 405