caa a22 4500 606187596 CHVBK 20210128100841.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00405-014-3373-z doi (NATIONALLICENCE)springer-10.1007/s00405-014-3373-z Microanatomy of the tympanic membrane in chronic myringitis obtained with optical coherence tomography [Elektronische Daten] [Ellen Guder, Eva Lankenau, F. Fleischhauer, H. Schulz-Hildebrandt, G. Hüttmann, H. Pau, Tino Just] A microscope-based optical coherence tomography (OCT) device was used to assess the microanatomy of the tympanic membrane in patients with chronic myringitis. A prospective study was designed for this purpose. OCT measurements of the tympanic membrane were done on 11 patients with myringitis with a microscope-based spectral domain OCT system. The in vivo findings were compared with those findings of a control group consisting of 36 patients with retraction pockets or atrophic tympanic membranes (n=13), myringosclerosis (n=12) and perforations (n=11). In active chronic myringitis, the thickness of the tympanic membrane is increased compared to healthy membranes and to other pathological conditions of the tympanic membrane. Consistent changes of the microanatomy of the tympanic membrane were found in chronic myringitis with OCT. Serial OCT measurements revealed no biofilm suspicious findings in all patients with active chronic myringitis. Intraoperative and in vivo OCT measurements may help to detect microanatomical changes of the tympanic membrane in chronic myringitis and in other conditions of the tympanic membrane. Springer-Verlag Berlin Heidelberg, 2014 Optical coherence tomography nationallicence Tympanic membrane nationallicence Chronic myringitis nationallicence Guder Ellen Department of Otorhinolaryngology, Head and Neck Surgery, University of Rostock, Doberaner Strasse 137-139, 18057, Rostock, Germany aut Lankenau Eva Institute for Biomedical Optics, University of Lübeck, Peter-Monnik-Weg 4, Lübeck, Germany aut Fleischhauer F. Institute for Biomedical Optics, University of Lübeck, Peter-Monnik-Weg 4, Lübeck, Germany aut Schulz-Hildebrandt H. Institute for Biomedical Optics, University of Lübeck, Peter-Monnik-Weg 4, Lübeck, Germany aut Hüttmann G. Institute for Biomedical Optics, University of Lübeck, Peter-Monnik-Weg 4, Lübeck, Germany aut Pau H. Department of Otorhinolaryngology, Head and Neck Surgery, University of Rostock, Doberaner Strasse 137-139, 18057, Rostock, Germany aut Just Tino Department of Otorhinolaryngology, Head and Neck Surgery, University of Rostock, Doberaner Strasse 137-139, 18057, Rostock, Germany aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/11(2015-11-01), 3217-3223 0937-4477 272:11<3217 2015 272 405 https://doi.org/10.1007/s00405-014-3373-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3373-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Guder Ellen Department of Otorhinolaryngology, Head and Neck Surgery, University of Rostock, Doberaner Strasse 137-139, 18057, Rostock, Germany aut NATIONALLICENCE 700 1- Lankenau Eva Institute for Biomedical Optics, University of Lübeck, Peter-Monnik-Weg 4, Lübeck, Germany aut NATIONALLICENCE 700 1- Fleischhauer F. Institute for Biomedical Optics, University of Lübeck, Peter-Monnik-Weg 4, Lübeck, Germany aut NATIONALLICENCE 700 1- Schulz-Hildebrandt H. Institute for Biomedical Optics, University of Lübeck, Peter-Monnik-Weg 4, Lübeck, Germany aut NATIONALLICENCE 700 1- Hüttmann G. Institute for Biomedical Optics, University of Lübeck, Peter-Monnik-Weg 4, Lübeck, Germany aut NATIONALLICENCE 700 1- Pau H. Department of Otorhinolaryngology, Head and Neck Surgery, University of Rostock, Doberaner Strasse 137-139, 18057, Rostock, Germany aut NATIONALLICENCE 700 1- Just Tino Department of Otorhinolaryngology, Head and Neck Surgery, University of Rostock, Doberaner Strasse 137-139, 18057, Rostock, Germany aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/11(2015-11-01), 3217-3223 0937-4477 272:11<3217 2015 272 405