caa a22 4500 606187669 CHVBK 20210128100841.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00405-014-3444-1 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3444-1 Efficacy of sublingual immunotherapy for house dust mite allergic rhinitis [Elektronische Daten] [Cemal Cingi, Nuray Bayar Muluk, Seçkin Ulusoy, Mustafa Acar, Seher Şirin, Bengü Çobanoğlu, Leman Birdane, Çiğdem Kalaycık, Burak Çakır, Fatih Oğhan, Sevilay Aynacı, Nagehan Erdoğmuş, Ömürsen Yıldırım, Ethem Şahin, Fuat Bulut, Mehmet Aksoy, Nurullah Türe, Cengiz Bal] In the present study, we investigated the outcomes of sublingual immunotherapy (SLIT) in house dust mite-induced allergic rhinitis (HDM-AR) patients. In this prospective, multicentric study, 186 patients with AR who had positive skin prick test results for HDMs were included. The patients were administered SLIT using Staloral 300 for 1year. Evaluation of the patients regarding symptom scores, clinical findings and Rhinitis Quality of Life Questionnaire (RQLQ) scores was performed at baseline, and then at 6 and 12months of therapy. Our results showed that, for all of the evaluated items (symptom scores, clinical findings and RQLQ scores), 12-month values were significantly lower than those at 6months and baseline. Similarly, 6-month values were significantly lower than those at baseline. There were no complications in any of our patients. SLIT for HDM-AR is a treatment modality that can be used safely. We obtained better results than expected, and the treatment showed a positive psychological effect; the patients believed that SLIT was the final step of treatment and, which made them feel better. Springer-Verlag Berlin Heidelberg, 2014 Sublingual immunotherapy (SLIT) nationallicence Allergic rhinitis (AR) nationallicence Rhinitis Quality of Life Questionnaire (RQLQ) nationallicence House dust mite (HDM) nationallicence Cingi Cemal ENT Department, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey aut Bayar Muluk Nuray ENT Department, Medical Faculty, Kırıkkale University, Kırıkkale, Turkey aut Ulusoy Seçkin ENT Clinics, Gaziosmanpaşa Taksim Ilkyardım Training and Research Hospital, TR Ministry of Health, Istanbul, Turkey aut Acar Mustafa ENT Clinics, Yunus Emre State Hospital, TR Ministry of Health, Eskisehir, Turkey aut Şirin Seher ENT Clinics, Derince Training and Research Hospital, TR Ministry of Health, Derince, Turkey aut Çobanoğlu Bengü ENT Clinics, Trabzon Training and Research Hospital, TR Ministry of Health, Trabzon, Turkey aut Birdane Leman ENT Clinics, Yunus Emre State Hospital, TR Ministry of Health, Eskisehir, Turkey aut Kalaycık Çiğdem ENT Department, Medical Faculty, Başkent University, Istanbul, Turkey aut Çakır Burak Anatomica Ear Nose Throat Clinic, Istanbul, Turkey aut Oğhan Fatih ENT Department, Medical Faculty, Kütahya Dumlupınar University, Kütahya, Turkey aut Aynacı Sevilay ENT Clinics, Eskişehir State Hospital, TR Ministry of Health, Eskisehir, Turkey aut Erdoğmuş Nagehan ENT Clinics, Osmaniye State Hospital, TR Ministry of Health, Osmaniye, Turkey aut Yıldırım Ömürsen ENT Clinics, Iğdır State Hospital, TR Ministry of Health, Iğdır, Turkey aut Şahin Ethem ENT Clinics, Bayındır İstanbul Hospital, Istanbul, Turkey aut Bulut Fuat ENT Clinics, Diyarbakır Memorial Hospital, Diyarbakır, Turkey aut Aksoy Mehmet ENT Department, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey aut Türe Nurullah ENT Department, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey aut Bal Cengiz Biostatistics Department, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/11(2015-11-01), 3341-3346 0937-4477 272:11<3341 2015 272 405 https://doi.org/10.1007/s00405-014-3444-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3444-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cingi Cemal ENT Department, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey aut NATIONALLICENCE 700 1- Bayar Muluk Nuray ENT Department, Medical Faculty, Kırıkkale University, Kırıkkale, Turkey aut NATIONALLICENCE 700 1- Ulusoy Seçkin ENT Clinics, Gaziosmanpaşa Taksim Ilkyardım Training and Research Hospital, TR Ministry of Health, Istanbul, Turkey aut NATIONALLICENCE 700 1- Acar Mustafa ENT Clinics, Yunus Emre State Hospital, TR Ministry of Health, Eskisehir, Turkey aut NATIONALLICENCE 700 1- Şirin Seher ENT Clinics, Derince Training and Research Hospital, TR Ministry of Health, Derince, Turkey aut NATIONALLICENCE 700 1- Çobanoğlu Bengü ENT Clinics, Trabzon Training and Research Hospital, TR Ministry of Health, Trabzon, Turkey aut NATIONALLICENCE 700 1- Birdane Leman ENT Clinics, Yunus Emre State Hospital, TR Ministry of Health, Eskisehir, Turkey aut NATIONALLICENCE 700 1- Kalaycık Çiğdem ENT Department, Medical Faculty, Başkent University, Istanbul, Turkey aut NATIONALLICENCE 700 1- Çakır Burak Anatomica Ear Nose Throat Clinic, Istanbul, Turkey aut NATIONALLICENCE 700 1- Oğhan Fatih ENT Department, Medical Faculty, Kütahya Dumlupınar University, Kütahya, Turkey aut NATIONALLICENCE 700 1- Aynacı Sevilay ENT Clinics, Eskişehir State Hospital, TR Ministry of Health, Eskisehir, Turkey aut NATIONALLICENCE 700 1- Erdoğmuş Nagehan ENT Clinics, Osmaniye State Hospital, TR Ministry of Health, Osmaniye, Turkey aut NATIONALLICENCE 700 1- Yıldırım Ömürsen ENT Clinics, Iğdır State Hospital, TR Ministry of Health, Iğdır, Turkey aut NATIONALLICENCE 700 1- Şahin Ethem ENT Clinics, Bayındır İstanbul Hospital, Istanbul, Turkey aut NATIONALLICENCE 700 1- Bulut Fuat ENT Clinics, Diyarbakır Memorial Hospital, Diyarbakır, Turkey aut NATIONALLICENCE 700 1- Aksoy Mehmet ENT Department, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey aut NATIONALLICENCE 700 1- Türe Nurullah ENT Department, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey aut NATIONALLICENCE 700 1- Bal Cengiz Biostatistics Department, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/11(2015-11-01), 3341-3346 0937-4477 272:11<3341 2015 272 405