caa a22 4500 606190457 CHVBK 20210128100855.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s10577-015-9493-5 doi (NATIONALLICENCE)springer-10.1007/s10577-015-9493-5 Evolutionary impact of transposable elements on genomic diversity and lineage-specific innovation in vertebrates [Elektronische Daten] [Ian Warren, Magali Naville, Domitille Chalopin, Perrine Levin, Chloé Berger, Delphine Galiana, Jean-Nicolas Volff] Since their discovery, a growing body of evidence has emerged demonstrating that transposable elements are important drivers of species diversity. These mobile elements exhibit a great variety in structure, size and mechanisms of transposition, making them important putative actors in organism evolution. The vertebrates represent a highly diverse and successful lineage that has adapted to a wide range of different environments. These animals also possess a rich repertoire of transposable elements, with highly diverse content between lineages and even between species. Here, we review how transposable elements are driving genomic diversity and lineage-specific innovation within vertebrates. We discuss the large differences in TE content between different vertebrate groups and then go on to look at how they affect organisms at a variety of levels: from the structure of chromosomes to their involvement in the regulation of gene expression, as well as in the formation and evolution of non-coding RNAs and protein-coding genes. In the process of doing this, we highlight how transposable elements have been involved in the evolution of some of the key innovations observed within the vertebrate lineage, driving the group's diversity and success. Springer Science+Business Media Dordrecht, 2015 Transposable elements nationallicence Diversity nationallicence Vertebrates nationallicence Lineage-specific evolution nationallicence New genes nationallicence ChIP-Seq : Chromatin immunoprecipitation sequencing nationallicence ERV : Endogenous retrovirus nationallicence ESC : Embryonic stem cell nationallicence HTT : Horizontal transfer of TEs nationallicence LINE (or SINE) : Long (or short) interspersed nuclear element nationallicence lncRNA : Long non-coding RNA nationallicence LTR : Long terminal repeat nationallicence MYA : Million years ago nationallicence Myr : Million years nationallicence nt : Nucleotides nationallicence TE : Transposable element nationallicence Warren Ian Institut de Génomique Fonctionnelle de Lyon, CNRS UMR5242, Ecole Normale Supérieure de Lyon, Lyon, France aut Naville Magali Institut de Génomique Fonctionnelle de Lyon, CNRS UMR5242, Ecole Normale Supérieure de Lyon, Lyon, France aut Chalopin Domitille Institut de Génomique Fonctionnelle de Lyon, CNRS UMR5242, Ecole Normale Supérieure de Lyon, Lyon, France aut Levin Perrine Institut de Génomique Fonctionnelle de Lyon, CNRS UMR5242, Ecole Normale Supérieure de Lyon, Lyon, France aut Berger Chloé Institut de Génomique Fonctionnelle de Lyon, CNRS UMR5242, Ecole Normale Supérieure de Lyon, Lyon, France aut Galiana Delphine Institut de Génomique Fonctionnelle de Lyon, CNRS UMR5242, Ecole Normale Supérieure de Lyon, Lyon, France aut Volff Jean-Nicolas Institut de Génomique Fonctionnelle de Lyon, CNRS UMR5242, Ecole Normale Supérieure de Lyon, Lyon, France aut Chromosome Research Springer Netherlands 23/3(2015-09-01), 505-531 0967-3849 23:3<505 2015 23 10577 https://doi.org/10.1007/s10577-015-9493-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10577-015-9493-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Warren Ian Institut de Génomique Fonctionnelle de Lyon, CNRS UMR5242, Ecole Normale Supérieure de Lyon, Lyon, France aut NATIONALLICENCE 700 1- Naville Magali Institut de Génomique Fonctionnelle de Lyon, CNRS UMR5242, Ecole Normale Supérieure de Lyon, Lyon, France aut NATIONALLICENCE 700 1- Chalopin Domitille Institut de Génomique Fonctionnelle de Lyon, CNRS UMR5242, Ecole Normale Supérieure de Lyon, Lyon, France aut NATIONALLICENCE 700 1- Levin Perrine Institut de Génomique Fonctionnelle de Lyon, CNRS UMR5242, Ecole Normale Supérieure de Lyon, Lyon, France aut NATIONALLICENCE 700 1- Berger Chloé Institut de Génomique Fonctionnelle de Lyon, CNRS UMR5242, Ecole Normale Supérieure de Lyon, Lyon, France aut NATIONALLICENCE 700 1- Galiana Delphine Institut de Génomique Fonctionnelle de Lyon, CNRS UMR5242, Ecole Normale Supérieure de Lyon, Lyon, France aut NATIONALLICENCE 700 1- Volff Jean-Nicolas Institut de Génomique Fonctionnelle de Lyon, CNRS UMR5242, Ecole Normale Supérieure de Lyon, Lyon, France aut NATIONALLICENCE 773 0- Chromosome Research Springer Netherlands 23/3(2015-09-01), 505-531 0967-3849 23:3<505 2015 23 10577