caa a22 4500 60619049X CHVBK 20210128100855.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s10577-015-9491-7 doi (NATIONALLICENCE)springer-10.1007/s10577-015-9491-7 Transposable elements and G-quadruplexes [Elektronische Daten] [Eduard Kejnovsky, Viktor Tokan, Matej Lexa] A significant part of eukaryotic genomes is formed by transposable elements (TEs) containing not only genes but also regulatory sequences. Some of the regulatory sequences located within TEs can form secondary structures like hairpins or three-stranded (triplex DNA) and four-stranded (quadruplex DNA) conformations. This review focuses on recent evidence showing that G-quadruplex-forming sequences in particular are often present in specific parts of TEs in plants and humans. We discuss the potential role of these structures in the TE life cycle as well as the impact of G-quadruplexes on replication, transcription, translation, chromatin status, and recombination. The aim of this review is to emphasize that TEs may serve as vehicles for the genomic spread of G-quadruplexes. These non-canonical DNA structures and their conformational switches may constitute another regulatory system that, together with small and long non-coding RNA molecules and proteins, contribute to the complex cellular network resulting in the large diversity of eukaryotes. Springer Science+Business Media Dordrecht, 2015 transposable elements nationallicence LTR retrotransposons nationallicence DNA and RNA quadruplexes nationallicence G-quadruplexes nationallicence transcription nationallicence recombination nationallicence replication nationallicence TEs : Transposable elements nationallicence LTR : Long terminal repeat nationallicence PQS : Potential quadruplex-forming sequence nationallicence Kejnovsky Eduard Department of Plant Developmental Genetics, Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic aut Tokan Viktor Department of Plant Developmental Genetics, Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic aut Lexa Matej Faculty of Informatics, Masaryk University Brno, Brno, Czech Republic aut Chromosome Research Springer Netherlands 23/3(2015-09-01), 615-623 0967-3849 23:3<615 2015 23 10577 https://doi.org/10.1007/s10577-015-9491-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10577-015-9491-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kejnovsky Eduard Department of Plant Developmental Genetics, Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic aut NATIONALLICENCE 700 1- Tokan Viktor Department of Plant Developmental Genetics, Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic aut NATIONALLICENCE 700 1- Lexa Matej Faculty of Informatics, Masaryk University Brno, Brno, Czech Republic aut NATIONALLICENCE 773 0- Chromosome Research Springer Netherlands 23/3(2015-09-01), 615-623 0967-3849 23:3<615 2015 23 10577