caa a22 4500 606200215 CHVBK 20210128100942.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s10653-015-9724-x doi (NATIONALLICENCE)springer-10.1007/s10653-015-9724-x Investigating relationships between biomarkers of exposure and environmental copper and manganese levels in house dusts from a Portuguese industrial city [Elektronische Daten] [A. Reis, S. Costa, I. Santos, C. Patinha, Y. Noack, J. Wragg, M. Cave, A. Sousa] This study reports on data obtained from a pilot survey focusing on house dust and toenail metal(loids) concentrations in residents living in the industrial city of Estarreja. The study design hereby described aims at investigating relationships between human toenails and both copper and manganese levels in settledhouse dusts. A total of 21 households and 30 individuals were recruited for the pilot study: 19 households corresponding to 27 residents living near the industrial complex, forming the exposed group, plus 2 households and 3 residents from residential areas with no anticipated environmental contaminants that were used for comparison. Factorial analysis was used for source identification purposes. Investigation on the potential influence of environmental factors over copper and manganese levels in the toenails was carried out via questionnaire data and multiple correspondence analysis. The results show that copper concentrations are more elevated in the indoor dusts, while manganese concentrations are more elevated in the outdoor dust samples. The geometrical relationships in the datasets suggest that the backyard soil is a probable source of manganese to the indoor dust. Copper and manganese contents in the toenail clippings are more elevated in children than in adults, but the difference between the two age groups is not statistically significant (p>0.05). Investigation of environmental factors influencing the exposure-biomarker association indicates a probable relationship between manganese contents in indoor dust and manganese levels in toenail clippings, a result that is partially supported by the bioaccessibility estimates. However, for copper, no relationship was found between indoor dusts and the biomarkers of exposure. Springer Science+Business Media Dordrecht, 2015 House dust nationallicence Toenail clippings nationallicence Copper nationallicence Manganese nationallicence Factorial analysis nationallicence Reis A. GEOBIOTEC, Departmento de Geociências, Campus Universitário de Santiago, Universidade de Aveiro, 3810-193, Aveiro, Portugal aut Costa S. GEOBIOTEC, Departmento de Geociências, Campus Universitário de Santiago, Universidade de Aveiro, 3810-193, Aveiro, Portugal aut Santos I. GEOBIOTEC, Departmento de Geociências, Campus Universitário de Santiago, Universidade de Aveiro, 3810-193, Aveiro, Portugal aut Patinha C. GEOBIOTEC, Departmento de Geociências, Campus Universitário de Santiago, Universidade de Aveiro, 3810-193, Aveiro, Portugal aut Noack Y. CNRS, CEREGE, UMR 7330, Aix-Marseille Université, BP 80, 13545, Aix en Provence Cedex 4, France aut Wragg J. British Geological Survey, NG12 5GG, Keyworth, Nottingham, UK aut Cave M. British Geological Survey, NG12 5GG, Keyworth, Nottingham, UK aut Sousa A. CERENA, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001, Lisboa, Portugal aut Environmental Geochemistry and Health Springer Netherlands 37/4(2015-08-01), 725-744 0269-4042 37:4<725 2015 37 10653 https://doi.org/10.1007/s10653-015-9724-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10653-015-9724-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Reis A. GEOBIOTEC, Departmento de Geociências, Campus Universitário de Santiago, Universidade de Aveiro, 3810-193, Aveiro, Portugal aut NATIONALLICENCE 700 1- Costa S. GEOBIOTEC, Departmento de Geociências, Campus Universitário de Santiago, Universidade de Aveiro, 3810-193, Aveiro, Portugal aut NATIONALLICENCE 700 1- Santos I. GEOBIOTEC, Departmento de Geociências, Campus Universitário de Santiago, Universidade de Aveiro, 3810-193, Aveiro, Portugal aut NATIONALLICENCE 700 1- Patinha C. GEOBIOTEC, Departmento de Geociências, Campus Universitário de Santiago, Universidade de Aveiro, 3810-193, Aveiro, Portugal aut NATIONALLICENCE 700 1- Noack Y. CNRS, CEREGE, UMR 7330, Aix-Marseille Université, BP 80, 13545, Aix en Provence Cedex 4, France aut NATIONALLICENCE 700 1- Wragg J. British Geological Survey, NG12 5GG, Keyworth, Nottingham, UK aut NATIONALLICENCE 700 1- Cave M. British Geological Survey, NG12 5GG, Keyworth, Nottingham, UK aut NATIONALLICENCE 700 1- Sousa A. CERENA, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001, Lisboa, Portugal aut NATIONALLICENCE 773 0- Environmental Geochemistry and Health Springer Netherlands 37/4(2015-08-01), 725-744 0269-4042 37:4<725 2015 37 10653