caa a22 4500 606201106 CHVBK 20210128100946.0 cr unu---uuuuu 210128e20150101xx s 000 0 eng 10.1007/s00429-013-0639-y doi (NATIONALLICENCE)springer-10.1007/s00429-013-0639-y MRI anatomical variants of mammillary bodies [Elektronische Daten] [Micaela Tagliamonte, Carlo Sestieri, Gian Romani, Massimo Gallucci, Massimo Caulo] The mammillary bodies (MBs) are classically defined as a pair of small round structures located on the undersurface of the diencephalon. The systematic observation of MR brain images of patients with neurological diseases, but also of healthy subjects enrolled in research protocols, reveals, however, a greater anatomical variability. The aim of the present study was to define the spectrum of such variability using spatial normalized 3D TFE T1-weighted MR images in a group of 151 healthy right-handed young subjects (78 females, age range 16-39years). The MBs were identified on reformatted coronal and axial images and classified according to morphological, positional and numerical criteria. On the basis of coronal images, MBs were first divided into symmetrical (86.1%) and asymmetrical (13.9%), depending on their respective height. Symmetrical MBs were further subdivided into three variants [type A (2.7%), B (76.2%), C (7.3%)] according to the depth of the intermammillary sulcus. Two morphological variants were defined on axial images, depending on whether the MBs were circular (63.6%) or elliptic (36.4%). This latter group was further divided in two subgroups, depending on whether the MBs were parallel (21.9%) or convergent (14.6%). Finally, two subjects (1.3%) presented a supernumeral MB. The transverse size of the third ventricle was greater in the type A compared to the type B and C groups. Gender did not significantly affect the frequency of MBs variants, except for the three symmetrical subgroups in which the variants A and C were more frequent in males than in females. These findings suggest the presence of an anatomical variability of the MBs, in contrast to their classical definition. Therefore, atypical presentation of MBs can be the expression of this variability rather than a marker of neurological disorders (i.e. cerebral malformation, mesial temporal sclerosis, Wernicke-Korsakoff syndrome). Springer-Verlag Berlin Heidelberg, 2013 Mammillary bodies nationallicence Anatomical variant nationallicence MRI nationallicence Tagliamonte Micaela Institute Advanced Biomedical Technologies (ITAB), University "G. d'Annunzio” Chieti-Pescara, Via dei Vestini 33, 66100, Chieti, Italy aut Sestieri Carlo Institute Advanced Biomedical Technologies (ITAB), University "G. d'Annunzio” Chieti-Pescara, Via dei Vestini 33, 66100, Chieti, Italy aut Romani Gian Institute Advanced Biomedical Technologies (ITAB), University "G. d'Annunzio” Chieti-Pescara, Via dei Vestini 33, 66100, Chieti, Italy aut Gallucci Massimo Department on Neuroradiology, University of L'Aquila, L'Aquila, Italy aut Caulo Massimo Institute Advanced Biomedical Technologies (ITAB), University "G. d'Annunzio” Chieti-Pescara, Via dei Vestini 33, 66100, Chieti, Italy aut Brain Structure and Function Springer Berlin Heidelberg 220/1(2015-01-01), 85-90 1863-2653 220:1<85 2015 220 429 https://doi.org/10.1007/s00429-013-0639-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 brief-communication jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00429-013-0639-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tagliamonte Micaela Institute Advanced Biomedical Technologies (ITAB), University "G. d'Annunzio” Chieti-Pescara, Via dei Vestini 33, 66100, Chieti, Italy aut NATIONALLICENCE 700 1- Sestieri Carlo Institute Advanced Biomedical Technologies (ITAB), University "G. d'Annunzio” Chieti-Pescara, Via dei Vestini 33, 66100, Chieti, Italy aut NATIONALLICENCE 700 1- Romani Gian Institute Advanced Biomedical Technologies (ITAB), University "G. d'Annunzio” Chieti-Pescara, Via dei Vestini 33, 66100, Chieti, Italy aut NATIONALLICENCE 700 1- Gallucci Massimo Department on Neuroradiology, University of L'Aquila, L'Aquila, Italy aut NATIONALLICENCE 700 1- Caulo Massimo Institute Advanced Biomedical Technologies (ITAB), University "G. d'Annunzio” Chieti-Pescara, Via dei Vestini 33, 66100, Chieti, Italy aut NATIONALLICENCE 773 0- Brain Structure and Function Springer Berlin Heidelberg 220/1(2015-01-01), 85-90 1863-2653 220:1<85 2015 220 429