caa a22 4500 606201211 CHVBK 20210128100947.0 cr unu---uuuuu 210128e20150101xx s 000 0 eng 10.1007/s00429-013-0637-0 doi (NATIONALLICENCE)springer-10.1007/s00429-013-0637-0 Discordant cerebral lateralisation for verbal fluency is not an artefact of attention: evidence from MzHd twins [Elektronische Daten] [Jennifer Gurd, Patricia Cowell] The current study investigated how the brain structure-function relationships between covert and overt verbal fluency in monozygotic handedness discordant (MzHd) twins relates to broader attentional measures. Evidence presented here shows that the structure-function correlation demonstrated between functional cerebral lateralisation and corpus callosum widths 22-39, contiguous with Broca's area and the middle frontal gyri (Gurd et al. in Brain Struct Funct 218:491-509, 2013), is not an artefact of attention. Twenty-five pairs of female MzHd twins performed a verbal switching task titrated for number of switches. The paradigm permits calculation of switch rates and costs. The switch rate and cost varied as a function of number of switches (1, 2, 3). There were no differences in any measure in relation to right-left handedness in twin pairs. This was supported by large and significant within-twin pair correlations. Atypical functional lateralisation of inferior and middle frontal lobes does not appear to be associated with better or worse performance on verbal task-switching. Discordant lateralisation for verbal fluency does not predict behavioural performance profiles in MzHd twins. This evidence is compatible with a view that attentional components of verbal fluency task performance may have significant heritable components. It does not indicate that neural correlates of frontal cerebral laterality for verbal fluency in MzHd twins are significantly accountable for by heritable components. Springer-Verlag Berlin Heidelberg, 2013 Attention nationallicence Verbal fluency nationallicence Twins nationallicence Corpus callosum nationallicence fMRI nationallicence Task-switching nationallicence Gurd Jennifer Nuffield Department of Clinical Neurosciences, Level 6, The West Wing, John Radcliffe Hospital, University of Oxford, OX3 9DU, Oxford, UK aut Cowell Patricia Department of Human Communication Sciences, University of Sheffield, Sheffield, UK aut Brain Structure and Function Springer Berlin Heidelberg 220/1(2015-01-01), 59-69 1863-2653 220:1<59 2015 220 429 https://doi.org/10.1007/s00429-013-0637-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00429-013-0637-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gurd Jennifer Nuffield Department of Clinical Neurosciences, Level 6, The West Wing, John Radcliffe Hospital, University of Oxford, OX3 9DU, Oxford, UK aut NATIONALLICENCE 700 1- Cowell Patricia Department of Human Communication Sciences, University of Sheffield, Sheffield, UK aut NATIONALLICENCE 773 0- Brain Structure and Function Springer Berlin Heidelberg 220/1(2015-01-01), 59-69 1863-2653 220:1<59 2015 220 429