caa a22 4500 606201815 CHVBK 20210128100950.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00429-014-0847-0 doi (NATIONALLICENCE)springer-10.1007/s00429-014-0847-0 Parallel and serial processing in dual-tasking differentially involves mechanisms in the striatum and the lateral prefrontal cortex [Elektronische Daten] [Ali Yildiz, Christian Beste] The lateral prefrontal cortex and the basal ganglia are known to be important for response selection processes, also in dual-task situations. However, response selection in dual-task situations can be achieved using different modes ranging from a parallel selection to a more serial selection of responses. Nothing is known whether differences in these processing modes during dual-tasking have distinct functional neuroanatomical correlates. In this fMRI study we analyzed performance in a psychological refractory period paradigm. In this paradigm we design a PRP task where we vary the frequency of short and long stimulus onset asynchronies between the two tasks. Using mathematical constraints we interpret the effects of this manipulation with respect to processing modes ranging from more serial to more parallel response selection. Contrastingly these blocks showed that response selection in dual-tasking under the constraint of more parallel processing is mediated by mechanisms operating at the striatal level, while response selection under the constraint of more serial processing is mediated via mechanisms operating in the lateral prefrontal cortex. The results suggest that lateral prefrontal and striatal regions are ‘optimized' for a certain processing modes in dual tasking. Springer-Verlag Berlin Heidelberg, 2014 Basal ganglia nationallicence Response selection nationallicence fMRI nationallicence Serial processing nationallicence Parallel processing nationallicence Dual-tasking nationallicence Lateral prefrontal cortex nationallicence Yildiz Ali Cognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine of the TU Dresden, Schubertstrasse 42, 01309, Dresden, Germany aut Beste Christian Cognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine of the TU Dresden, Schubertstrasse 42, 01309, Dresden, Germany aut Brain Structure and Function Springer Berlin Heidelberg 220/6(2015-11-01), 3131-3142 1863-2653 220:6<3131 2015 220 429 https://doi.org/10.1007/s00429-014-0847-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00429-014-0847-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yildiz Ali Cognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine of the TU Dresden, Schubertstrasse 42, 01309, Dresden, Germany aut NATIONALLICENCE 700 1- Beste Christian Cognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine of the TU Dresden, Schubertstrasse 42, 01309, Dresden, Germany aut NATIONALLICENCE 773 0- Brain Structure and Function Springer Berlin Heidelberg 220/6(2015-11-01), 3131-3142 1863-2653 220:6<3131 2015 220 429