caa a22 4500 606202501 CHVBK 20210128100953.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s00429-014-0784-y doi (NATIONALLICENCE)springer-10.1007/s00429-014-0784-y Shared vs. specific brain activation changes in dyslexia after training of phonology, attention, or reading [Elektronische Daten] [Stefan Heim, Julia Pape-Neumann, Muna van Ermingen-Marbach, Moti Brinkhaus, Marion Grande] Whereas the neurobiological basis of developmental dyslexia has received substantial attention, only little is known about the processes in the brain during remediation. This holds in particular in light of recent findings on cognitive subtypes of dyslexia which suggest interactions between individual profiles, training methods, and also the task in the scanner. Therefore, we trained three groups of German dyslexic primary school children in the domains of phonology, attention, or visual word recognition. We compared neurofunctional changes after 4weeks of training in these groups to those in untrained normal readers in a reading task and in a task of visual attention. The overall reading improvement in the dyslexic children was comparable over groups. It was accompanied by substantial increase of the activation level in the visual word form area (VWFA) during a reading task inside the scanner. Moreover, there were activation increases that were unique for each training group in the reading task. In contrast, when children performed the visual attention task, shared training effects were found in the left inferior frontal sulcus and gyrus, which varied in amplitude between the groups. Overall, the data reveal that different remediation programmes matched to individual profiles of dyslexia may improve reading ability and commonly affect the VWFA in dyslexia as a shared part of otherwise distinct networks. Springer-Verlag Berlin Heidelberg, 2014 Visual word form area nationallicence VWFA nationallicence Inferior occipito-temporal cortex nationallicence Ventral inferior temporal nationallicence Cortex nationallicence Phonological awareness nationallicence Grapheme nationallicence Phoneme nationallicence Children nationallicence Attention nationallicence Visual nationallicence Heim Stefan Department of Psychiatry, Psychotherapy, and Psychosomatics, Uniklinik RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany aut Pape-Neumann Julia Section Clinical and Cognitive Neurosciences, Department of Neurology, Uniklinik RWTH Aachen, Aachen, Germany aut van Ermingen-Marbach Muna Department of Psychiatry, Psychotherapy, and Psychosomatics, Uniklinik RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany aut Brinkhaus Moti Section Clinical and Cognitive Neurosciences, Department of Neurology, Uniklinik RWTH Aachen, Aachen, Germany aut Grande Marion Section Clinical and Cognitive Neurosciences, Department of Neurology, Uniklinik RWTH Aachen, Aachen, Germany aut Brain Structure and Function Springer Berlin Heidelberg 220/4(2015-07-01), 2191-2207 1863-2653 220:4<2191 2015 220 429 https://doi.org/10.1007/s00429-014-0784-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00429-014-0784-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Heim Stefan Department of Psychiatry, Psychotherapy, and Psychosomatics, Uniklinik RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany aut NATIONALLICENCE 700 1- Pape-Neumann Julia Section Clinical and Cognitive Neurosciences, Department of Neurology, Uniklinik RWTH Aachen, Aachen, Germany aut NATIONALLICENCE 700 1- van Ermingen-Marbach Muna Department of Psychiatry, Psychotherapy, and Psychosomatics, Uniklinik RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany aut NATIONALLICENCE 700 1- Brinkhaus Moti Section Clinical and Cognitive Neurosciences, Department of Neurology, Uniklinik RWTH Aachen, Aachen, Germany aut NATIONALLICENCE 700 1- Grande Marion Section Clinical and Cognitive Neurosciences, Department of Neurology, Uniklinik RWTH Aachen, Aachen, Germany aut NATIONALLICENCE 773 0- Brain Structure and Function Springer Berlin Heidelberg 220/4(2015-07-01), 2191-2207 1863-2653 220:4<2191 2015 220 429