caa a22 4500 60620296X CHVBK 20210128100955.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00429-014-0806-9 doi (NATIONALLICENCE)springer-10.1007/s00429-014-0806-9 A new myeloarchitectonic map of the human neocortex based on data from the Vogt-Vogt school [Elektronische Daten] [Rudolf Nieuwenhuys, Cees Broere, Leonardo Cerliani] The human cerebral cortex contains numerous myelinated fibres, the arrangement and density of which is by no means homogeneous throughout the cortex. Local differences in the spatial organization of these fibres render it possible to recognize areas with a different myeloarchitecture. The neuroanatomical subdiscipline aimed at the identification and delineation of such areas is known as myeloarchitectonics. During the period extending from 1910 to 1970, Oscar and Cécile Vogt and their numerous collaborators (The Vogt-Vogt school) published a large number of myeloarchitectonic studies on the cortex of the various lobes of the human cerebrum. Recently, one of us (Nieuwenhuys in Brain Struct Funct 218: 303-352, 2013) extensively reviewed these studies. It was concluded that the data available are adequate and sufficient for the composition of a myeloarchitectonic map of the entire human neocortex. The present paper is devoted to the creation of this map. Because the data provided by the Vogt-Vogt school are derived from many different brains, a standard brain had to be introduced to which all data available could be transferred. As such, the colin27 structural scan, aligned to the MNI305 template was selected. The procedure employed in this transfer involved computer-aided transformations of the lobar maps available in the literature, to the corresponding regions of the standard brain, as well as local adjustments in the border zones of the various lobes. The resultant map includes 180 myeloarchitectonic areas, 64 frontal, 30 parietal, 6 insular, 17 occipital and 63 temporal. The designation of the various areas with simple Arabic numbers, introduced by Oscar Vogt for the frontal and parietal cortices, has been extended over the entire neocortex. It may be expected that combination of the myeloarchitectonic data of the Vogt-Vogt school, as expressed in our map, with the results of the detailed cytoarchitectonic and receptor architectonic studies of Karl Zilles and Katrin Amunts and their numerous associates, will yield a comprehensive ‘supermap' of the structural organization of the human neocortex. For the time being, i. e., as long as this ‘supermap' is not yet available, our map may provide a tentative frame of reference for (a) the morphological interpretation of the results of functional neuroimaging studies; (b) the selection of starting points (seed voxels, regions-of-interest) in diffusion tractography studies and (c) the interpretation of putative myeloarchitectonic features, visualized by in vivo and ex vivo mappings of the cerebral cortex with high-field magnetic resonance imaging. Springer-Verlag Berlin Heidelberg, 2014 Architectonics nationallicence Cerebral cortex nationallicence Cytoarchitectonics nationallicence Myeloarchitectonics nationallicence Neuroimaging nationallicence Nissl technique nationallicence Weigert technique nationallicence acg : Anterior cingulate gyrus nationallicence ambg : Ambient gyrus nationallicence ang : Angular gyrus nationallicence aog : Anterior orbital gyrus nationallicence aos : Arcuate orbital sulcus nationallicence asg : Accessory short gyrus of insula nationallicence attg : Anterior transverse temporal gyrus nationallicence atts : Anterior transverse temporal sulcus nationallicence calcs : Calcarine sulcus nationallicence ces : Central sulcus nationallicence cesins : Central sulcus of insula nationallicence cisins : Circular sulcus of insula nationallicence cols : Collateral sulcus nationallicence cs : Cingulate sulcus nationallicence csab : Cingulate sulcus, ascending branch nationallicence cun : Cuneus nationallicence fg : Fasciolar gyrus nationallicence icg : Isthmus of cingular gyrus nationallicence ifg : Inferior frontal gyrus nationallicence ifgor : Inferior frontal gyrus, orbital part nationallicence ifgop : Inferior frontal gyrus, opercular part nationallicence ifgt : Inferior frontal gyrus, triangular part nationallicence ifs : Inferior frontal sulcus nationallicence ipl : Inferior parietal lobule nationallicence ips : Intraparietal sulcus nationallicence itg : Inferior temporal gyrus nationallicence its : Inferior temporal sulcus nationallicence lg1, 2 : First and second long gyrus of insula nationallicence log : Lateral orbital gyrus nationallicence los : Lateral orbital sulcus nationallicence lotg : Lateral occipitotemporal (fusiform) gyrus nationallicence ls : Lateral sulcus nationallicence lsab : Lateral sulcus, ascending branch nationallicence lsan : Lateral sulcus, anterior branch nationallicence lsp : Lateral sulcus, posterior branch nationallicence mfg : Middle frontal gyrus nationallicence mog : Medial orbital gyrus nationallicence mos : Medial orbital sulcus nationallicence motg : Medial occipitotemporal (lingual) gyrus nationallicence mtg : Middle temporal gyrus nationallicence mtps : Medial temporopolar sulcus nationallicence mtts : Middle transverse temporal sulcus nationallicence og : Occipital gyri nationallicence olfs : Olfactory sulcus nationallicence ots : Occipitotemporal sulcus nationallicence pcg : Posterior cingulate gyrus nationallicence pcl : Paracentral lobule nationallicence pcun : Precuneus nationallicence phg : Parahippocampal gyrus nationallicence pocg : Postcentral gyrus nationallicence pocs : Postcentral sulcus nationallicence pog : Posterior orbital gyrus nationallicence pos : Parieto-occipital sulcus nationallicence prcg : Precentral gyrus nationallicence prcs : Precentral sulcus nationallicence pron : Preoccipital notch nationallicence pttg : Posterior transverse temporal gyrus nationallicence ptts : Posterior transverse temporal sulcus nationallicence rhs : Rhinal sulcus nationallicence ris : Rostral inferior sulcus nationallicence rss : Rostral superior sulcus nationallicence sfg : Superior frontal gyrus nationallicence sfs : Superior frontal sulcus nationallicence sg1, 2, 3 : First, second and third short gyrus of insula nationallicence smg : Supramarginal gyrus nationallicence spl : Superior parietal lobule nationallicence stg : Superior temporal gyrus nationallicence strg : Straight gyrus nationallicence sts : Superior temporal sulcus nationallicence stsp : Superior temporal sulcus, posterior part nationallicence tp : Temporal plane nationallicence unc : Uncus of hippocampus nationallicence Nieuwenhuys Rudolf The Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands aut Broere Cees The Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands aut Cerliani Leonardo The Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands aut Brain Structure and Function Springer Berlin Heidelberg 220/5(2015-09-01), 2551-2573 1863-2653 220:5<2551 2015 220 429 https://doi.org/10.1007/s00429-014-0806-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00429-014-0806-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nieuwenhuys Rudolf The Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Broere Cees The Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Cerliani Leonardo The Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands aut NATIONALLICENCE 773 0- Brain Structure and Function Springer Berlin Heidelberg 220/5(2015-09-01), 2551-2573 1863-2653 220:5<2551 2015 220 429