caa a22 4500 606203117 CHVBK 20210128100956.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00429-014-0810-0 doi (NATIONALLICENCE)springer-10.1007/s00429-014-0810-0 Functional connectivity between right and left mesial temporal structures [Elektronische Daten] [Nuria Lacuey, Bilal Zonjy, Emine Kahriman, Farhad Kaffashi, Jonathan Miller, Hans Lüders] The aim of this study is to investigate functional connectivity between right and left mesial temporal structures using cerebrocerebral evoked potentials. We studied seven patients with drug-resistant focal epilepsy who were explored with stereotactically implanted depth electrodes in bilateral hippocampi. In all patients cerebrocerebral evoked potentials evoked by stimulation of the fornix were evaluated as part of a research project assessing fornix stimulation for control of hippocampal seizures. Stimulation of the fornix elicited responses in the ipsilateral hippocampus in all patients with a mean latency of 4.6ms (range 2-7ms). Two patients (29%) also had contralateral hippocampus responses with a mean latency of 7.5ms (range 5-12ms) and without involvement of the contralateral temporal neocortex or amygdala. This study confirms the existence of connections between bilateral mesial temporal structures in some patients and explains seizure discharge spreading between homotopic mesial temporal structures without neocortical involvement. Springer-Verlag Berlin Heidelberg, 2014 Functional connectivity nationallicence Fornix nationallicence Dorsal hippocampal commissure nationallicence Evoked potential nationallicence Epilepsy nationallicence Lacuey Nuria Epilepsy Center, UH Case Medical Center, 11100 Euclid Avenue, 44106, Cleveland, OH, USA aut Zonjy Bilal Epilepsy Center, UH Case Medical Center, 11100 Euclid Avenue, 44106, Cleveland, OH, USA aut Kahriman Emine Epilepsy Center, UH Case Medical Center, 11100 Euclid Avenue, 44106, Cleveland, OH, USA aut Kaffashi Farhad Epilepsy Center, UH Case Medical Center, 11100 Euclid Avenue, 44106, Cleveland, OH, USA aut Miller Jonathan Epilepsy Center, UH Case Medical Center, 11100 Euclid Avenue, 44106, Cleveland, OH, USA aut Lüders Hans Epilepsy Center, UH Case Medical Center, 11100 Euclid Avenue, 44106, Cleveland, OH, USA aut Brain Structure and Function Springer Berlin Heidelberg 220/5(2015-09-01), 2617-2623 1863-2653 220:5<2617 2015 220 429 https://doi.org/10.1007/s00429-014-0810-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00429-014-0810-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lacuey Nuria Epilepsy Center, UH Case Medical Center, 11100 Euclid Avenue, 44106, Cleveland, OH, USA aut NATIONALLICENCE 700 1- Zonjy Bilal Epilepsy Center, UH Case Medical Center, 11100 Euclid Avenue, 44106, Cleveland, OH, USA aut NATIONALLICENCE 700 1- Kahriman Emine Epilepsy Center, UH Case Medical Center, 11100 Euclid Avenue, 44106, Cleveland, OH, USA aut NATIONALLICENCE 700 1- Kaffashi Farhad Epilepsy Center, UH Case Medical Center, 11100 Euclid Avenue, 44106, Cleveland, OH, USA aut NATIONALLICENCE 700 1- Miller Jonathan Epilepsy Center, UH Case Medical Center, 11100 Euclid Avenue, 44106, Cleveland, OH, USA aut NATIONALLICENCE 700 1- Lüders Hans Epilepsy Center, UH Case Medical Center, 11100 Euclid Avenue, 44106, Cleveland, OH, USA aut NATIONALLICENCE 773 0- Brain Structure and Function Springer Berlin Heidelberg 220/5(2015-09-01), 2617-2623 1863-2653 220:5<2617 2015 220 429