caa a22 4500 606203370 CHVBK 20210128100957.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s00429-013-0703-7 doi (NATIONALLICENCE)springer-10.1007/s00429-013-0703-7 The surface area of early visual cortex predicts the amplitude of the visual evoked potential [Elektronische Daten] [Torbjørn Elvsåshagen, Torgeir Moberget, Erlend Bøen, Per Hol, Ulrik Malt, Stein Andersson, Lars Westlye] The extensive and increasing use of structural neuroimaging in the neurosciences rests on the assumption of an intimate relationship between structure and function in the human brain. However, few studies have examined the relationship between advanced magnetic resonance imaging (MRI) indices of cerebral structure and conventional measures of cerebral functioning in humans. Here we examined whether MRI-based morphometric measures of early visual cortex—estimated using a probabilistic anatomical mask of primary visual cortex (V1)—can predict the amplitude of the visual evoked potential (VEP), i.e., an electroencephalogram signal that primarily reflects postsynaptic potentials in early visual cortical areas. We found that left, right, and total V1 surface area positively predicted the VEP amplitude. In addition, we showed, using whole brain analysis of local surface areal expansion/contraction, that the association between VEP amplitude and surface area was highly specific for regions within bilateral V1. Together, these findings indicate a strong, selective relationship between MRI-based structural measures and functional properties of the human cerebral cortex. Springer-Verlag Berlin Heidelberg, 2014 Magnetic resonance imaging nationallicence Visual evoked potential nationallicence Visual cortex nationallicence Cortical thickness nationallicence Cortical surface area nationallicence Elvsåshagen Torbjørn Department of Psychosomatic Medicine, Oslo University Hospital, Rikshospitalet, Nydalen, Pb 4950, 0424, Oslo, Norway aut Moberget Torgeir Department of Psychosomatic Medicine, Oslo University Hospital, Rikshospitalet, Nydalen, Pb 4950, 0424, Oslo, Norway aut Bøen Erlend Department of Psychosomatic Medicine, Oslo University Hospital, Rikshospitalet, Nydalen, Pb 4950, 0424, Oslo, Norway aut Hol Per The Intervention Centre, Oslo University Hospital, Oslo, Norway aut Malt Ulrik Department of Psychosomatic Medicine, Oslo University Hospital, Rikshospitalet, Nydalen, Pb 4950, 0424, Oslo, Norway aut Andersson Stein Department of Psychosomatic Medicine, Oslo University Hospital, Rikshospitalet, Nydalen, Pb 4950, 0424, Oslo, Norway aut Westlye Lars Norwegian Centre for Mental Disorders Research (NORMENT), Oslo University Hospital, Oslo, Norway aut Brain Structure and Function Springer Berlin Heidelberg 220/2(2015-03-01), 1229-1236 1863-2653 220:2<1229 2015 220 429 https://doi.org/10.1007/s00429-013-0703-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 brief-communication jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00429-013-0703-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Elvsåshagen Torbjørn Department of Psychosomatic Medicine, Oslo University Hospital, Rikshospitalet, Nydalen, Pb 4950, 0424, Oslo, Norway aut NATIONALLICENCE 700 1- Moberget Torgeir Department of Psychosomatic Medicine, Oslo University Hospital, Rikshospitalet, Nydalen, Pb 4950, 0424, Oslo, Norway aut NATIONALLICENCE 700 1- Bøen Erlend Department of Psychosomatic Medicine, Oslo University Hospital, Rikshospitalet, Nydalen, Pb 4950, 0424, Oslo, Norway aut NATIONALLICENCE 700 1- Hol Per The Intervention Centre, Oslo University Hospital, Oslo, Norway aut NATIONALLICENCE 700 1- Malt Ulrik Department of Psychosomatic Medicine, Oslo University Hospital, Rikshospitalet, Nydalen, Pb 4950, 0424, Oslo, Norway aut NATIONALLICENCE 700 1- Andersson Stein Department of Psychosomatic Medicine, Oslo University Hospital, Rikshospitalet, Nydalen, Pb 4950, 0424, Oslo, Norway aut NATIONALLICENCE 700 1- Westlye Lars Norwegian Centre for Mental Disorders Research (NORMENT), Oslo University Hospital, Oslo, Norway aut NATIONALLICENCE 773 0- Brain Structure and Function Springer Berlin Heidelberg 220/2(2015-03-01), 1229-1236 1863-2653 220:2<1229 2015 220 429