caa a22 4500 606203532 CHVBK 20210128100958.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s00429-013-0680-x doi (NATIONALLICENCE)springer-10.1007/s00429-013-0680-x Descriptive anatomy of Heschl's gyri in 430 healthy volunteers, including 198 left-handers [Elektronische Daten] [D. Marie, G. Jobard, F. Crivello, G. Perchey, L. Petit, E. Mellet, M. Joliot, L. Zago, B. Mazoyer, N. Tzourio-Mazoyer] This study describes the gyrification patterns and surface areas of Heschl's gyrus (HG) in 430 healthy volunteers mapped with magnetic resonance imaging. Among the 232 right-handers, we found a large occurrence of duplication (64%), especially on the right (49 vs. 37% on the left). Partial duplication was twice more frequent on the left than complete duplication. On the opposite, in the right hemisphere, complete duplication was 10% more frequent than partial duplication. The most frequent inter-hemispheric gyrification patterns were bilateral single HG (36%) and left single-right duplication (27%). The least common patterns were left duplication-right single (22%) and bilateral duplication (15%). Duplication was associated with decreased anterior HG surface area on the corresponding side, independently of the type of duplication, and increased total HG surface area (including the second gyrus). Inter-hemispheric gyrification patterns strongly influenced both anterior and total HG surface area asymmetries, leftward asymmetry of the anterior HG surface was observed in all patterns except double left HG, and total HG surface asymmetry favored the side of duplication. Compared to right-handers, the 198 left-handers exhibited lower occurrence of duplication, and larger right anterior HG surface and total HG surface areas. Left-handers' HG surface asymmetries were thus significantly different from those of right-handers, with a loss of leftward asymmetry of their anterior HG surface, and with significant rightward asymmetry of their total HG surface. In summary, gyrification patterns have a strong impact on HG surface and asymmetry. The observed reduced lateralization of HG duplications and anterior HG asymmetry in left-handers highlights HG inter-hemispheric gyrification patterns as a potential candidate marker of speech lateralization. The Author(s), 2013 Heschl's gyrus nationallicence MRI nationallicence Anatomy nationallicence Handedness nationallicence Speech nationallicence Hemispheric specialization nationallicence Marie D. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut Jobard G. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut Crivello F. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut Perchey G. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut Petit L. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut Mellet E. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut Joliot M. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut Zago L. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut Mazoyer B. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut Tzourio-Mazoyer N. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut Brain Structure and Function Springer Berlin Heidelberg 220/2(2015-03-01), 729-743 1863-2653 220:2<729 2015 220 429 https://doi.org/10.1007/s00429-013-0680-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00429-013-0680-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Marie D. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut NATIONALLICENCE 700 1- Jobard G. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut NATIONALLICENCE 700 1- Crivello F. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut NATIONALLICENCE 700 1- Perchey G. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut NATIONALLICENCE 700 1- Petit L. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut NATIONALLICENCE 700 1- Mellet E. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut NATIONALLICENCE 700 1- Joliot M. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut NATIONALLICENCE 700 1- Zago L. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut NATIONALLICENCE 700 1- Mazoyer B. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut NATIONALLICENCE 700 1- Tzourio-Mazoyer N. GIN, UMR 5296, University Bordeaux, 33000, Bordeaux, France aut NATIONALLICENCE 773 0- Brain Structure and Function Springer Berlin Heidelberg 220/2(2015-03-01), 729-743 1863-2653 220:2<729 2015 220 429