caa a22 4500 606204385 CHVBK 20210128101002.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s10388-014-0435-7 doi (NATIONALLICENCE)springer-10.1007/s10388-014-0435-7 Long-term survival for advanced esophageal cancer patients with an esophago-bronchial fistula can be achieved by timely multimodality therapy [Elektronische Daten] [Takahiro Yoshida, Akira Tangoku, Yoshihito Furukita, Takeshi Nishino, Hirokazu Takechi, Yukikiyo Kawakami, Atsushi Morishita, Masami Morimoto, Satoshi Fujiwara, Seiya Inoue, Takuya Minato, Masakazu Goto, Yota Yamamoto, Yasuhiro Yuasa, Hiromichi Yamai, Junichi Seike, Takanori Miyoshi] We reported four consecutive advanced esophageal cancer patients with esophago-bronchial fistula (EBF) who were managed well and achieved long-term survival with timely multimodality therapy including bypass operation. Eighty-four patients with esophageal cancer located in the upper or middle esophagus who were treated in our institute from 2005 to 2013 were diagnosed with cT4 at the time of admission. Eight (9.5%) of those 84 cT4 patients developed the esophago-bronchial/tracheal fistula. Out of eight patients, four (50%) who responded to prior chemotherapy or chemoradiotherapy received esophageal bypass operations to manage their QOL and continue the following therapy. Not only nutrition and quality of life but also fighting spirit were maintained by allowing oral intake and resulted in completion of postoperative chemoradiotherapy in all 4 patients. Multimodality treatment including a bypass operation provided high QOL and long-term survival even in advanced esophageal cancer patients with EBFs. The Japan Esophageal Society and Springer Japan, 2014 Advanced esophageal cancer nationallicence Esophago-bronchial fistula nationallicence Multimodality therapy nationallicence Chemotherapy nationallicence Chemoradiotherapy nationallicence Bypass operation nationallicence Yoshida Takahiro Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Tangoku Akira Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Furukita Yoshihito Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Nishino Takeshi Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Takechi Hirokazu Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Kawakami Yukikiyo Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Morishita Atsushi Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Morimoto Masami Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Fujiwara Satoshi Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Inoue Seiya Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Minato Takuya Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Goto Masakazu Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Yamamoto Yota Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Yuasa Yasuhiro Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Yamai Hiromichi Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Seike Junichi Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Miyoshi Takanori Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut Esophagus Springer Japan 12/3(2015-07-01), 277-285 1612-9059 12:3<277 2015 12 10388 https://doi.org/10.1007/s10388-014-0435-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10388-014-0435-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yoshida Takahiro Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 700 1- Tangoku Akira Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 700 1- Furukita Yoshihito Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 700 1- Nishino Takeshi Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 700 1- Takechi Hirokazu Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 700 1- Kawakami Yukikiyo Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 700 1- Morishita Atsushi Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 700 1- Morimoto Masami Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 700 1- Fujiwara Satoshi Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 700 1- Inoue Seiya Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 700 1- Minato Takuya Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 700 1- Goto Masakazu Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 700 1- Yamamoto Yota Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 700 1- Yuasa Yasuhiro Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 700 1- Yamai Hiromichi Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 700 1- Seike Junichi Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 700 1- Miyoshi Takanori Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto cho, 770-8503, Tokushima, Japan aut NATIONALLICENCE 773 0- Esophagus Springer Japan 12/3(2015-07-01), 277-285 1612-9059 12:3<277 2015 12 10388