caa a22 4500 606204415 CHVBK 20210128101002.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s10388-014-0454-4 doi (NATIONALLICENCE)springer-10.1007/s10388-014-0454-4 Esophageal cancer associated with bilateral hilar lymphadenopathy caused by sarcoid-like reactions: a report of two cases [Elektronische Daten] [Yuki Bekki, Yasue Kimura, Masaru Morita, Yoko Zaitsu, Hiroshi Saeki, Tatsuro Okamoto, Eiji Oki, Shingo Baba, Yoshinao Oda, Yoshihiko Maehara] Hilar lymph node metastasis of esophageal cancer is considered to be a distant metastasis and is not indicated for surgical resection. However, its diagnosis is difficult when accompanied by inflammatory diseases such as sarcoidosis. We report two patients with esophageal cancer accompanied by bilateral hilar lymphadenopathy or accumulation on [18F]-fluorodeoxyglucose positron emission tomography-computed tomography. The first patient underwent surgery because the enlarged bilateral hilar lymph nodes were considered to be nonmalignant lesions owing to superficial carcinoma and symmetric distribution of the hilar lymph nodes. The second patient received chemotherapy, which caused the main tumor to shrink and decreased [18F]-fluorodeoxyglucose uptake. However, chemotherapy did not affect the hilar lymphadenopathy, which suggests that it was caused by reactive changes rather than metastasis. In both cases, esophagectomy and histological findings revealed that the hilar nodes were caused by sarcoid-like reactions. These findings profoundly influenced our treatment decisions for these patients. The Japan Esophageal Society and Springer Japan, 2014 Esophageal cancer nationallicence Hilar lymphadenopathy nationallicence FDG-PET/CT nationallicence Bekki Yuki Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut Kimura Yasue Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut Morita Masaru Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut Zaitsu Yoko Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut Saeki Hiroshi Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut Okamoto Tatsuro Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut Oki Eiji Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut Baba Shingo Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut Oda Yoshinao Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut Maehara Yoshihiko Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut Esophagus Springer Japan 12/3(2015-07-01), 322-326 1612-9059 12:3<322 2015 12 10388 https://doi.org/10.1007/s10388-014-0454-4 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10388-014-0454-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bekki Yuki Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut NATIONALLICENCE 700 1- Kimura Yasue Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut NATIONALLICENCE 700 1- Morita Masaru Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut NATIONALLICENCE 700 1- Zaitsu Yoko Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut NATIONALLICENCE 700 1- Saeki Hiroshi Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut NATIONALLICENCE 700 1- Okamoto Tatsuro Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut NATIONALLICENCE 700 1- Oki Eiji Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut NATIONALLICENCE 700 1- Baba Shingo Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut NATIONALLICENCE 700 1- Oda Yoshinao Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut NATIONALLICENCE 700 1- Maehara Yoshihiko Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, 812-8582, Fukuoka, Japan aut NATIONALLICENCE 773 0- Esophagus Springer Japan 12/3(2015-07-01), 322-326 1612-9059 12:3<322 2015 12 10388