caa a22 4500 606204466 CHVBK 20210128101002.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s10388-014-0419-7 doi (NATIONALLICENCE)springer-10.1007/s10388-014-0419-7 Biphasic synovial sarcoma of the cervical esophagus confirmed by the presence of SYT - SSX1 fusion transcripts [Elektronische Daten] [Masahiro Niihara, Hiroshi Sato, Kimihide Kusafuka, Satoshi Kamiya, Ryo Ashida, Takashi Nakajima, Yasuhiro Tsubosa] Synovial sarcoma of the digestive tract, including that of the esophagus, is extremely rare. To our knowledge, only 9 cases of primary synovial sarcoma of the esophagus have been reported worldwide. Here, we describe the case of a 70-year-old man who presented with dysphagia and hoarseness, which he had been experiencing for 4months. A pigmented polypoid mass was detected at the cervical esophagus and spindle cell sarcoma was suspected on the basis of biopsy findings. Two operations were performed to completely excise both the tumor and regional lymph nodes. The tumor was diagnosed as a biphasic synovial sarcoma on the basis of the detection of SYT-SSX1 fusion transcripts by reverse transcription-polymerase chain reaction and fluorescence in situ hybridization. Twenty-two months following surgery, the patient developed local recurrence and received radiotherapy with 60Gy in 30 fractions. Post-treatment follow-up uncovered the presence of left cervical lymph node metastases that were then removed. Approximately 1month after resection, multiple metastases developed in the lungs. At his request, the patient did not receive any chemotherapy and died at 42months after the first operation. The Japan Esophageal Society and Springer Japan, 2014 Esophagus nationallicence Sarcoma nationallicence SYT-SSX nationallicence RT-PCR nationallicence FISH nationallicence Niihara Masahiro Division of Esophageal Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, 411-8777, Nagaizumi, Shizuoka, Japan aut Sato Hiroshi Department of Esophagogastric Surgery, Saitama International Medical Center, Saitama Medical University, Saitama, Japan aut Kusafuka Kimihide Pathology Division, Shizuoka Cancer Center, Shizuoka, Japan aut Kamiya Satoshi Division of Esophageal Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, 411-8777, Nagaizumi, Shizuoka, Japan aut Ashida Ryo Division of Esophageal Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, 411-8777, Nagaizumi, Shizuoka, Japan aut Nakajima Takashi Pathology Division, Shizuoka Cancer Center, Shizuoka, Japan aut Tsubosa Yasuhiro Division of Esophageal Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, 411-8777, Nagaizumi, Shizuoka, Japan aut Esophagus Springer Japan 12/3(2015-07-01), 251-257 1612-9059 12:3<251 2015 12 10388 https://doi.org/10.1007/s10388-014-0419-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10388-014-0419-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Niihara Masahiro Division of Esophageal Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, 411-8777, Nagaizumi, Shizuoka, Japan aut NATIONALLICENCE 700 1- Sato Hiroshi Department of Esophagogastric Surgery, Saitama International Medical Center, Saitama Medical University, Saitama, Japan aut NATIONALLICENCE 700 1- Kusafuka Kimihide Pathology Division, Shizuoka Cancer Center, Shizuoka, Japan aut NATIONALLICENCE 700 1- Kamiya Satoshi Division of Esophageal Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, 411-8777, Nagaizumi, Shizuoka, Japan aut NATIONALLICENCE 700 1- Ashida Ryo Division of Esophageal Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, 411-8777, Nagaizumi, Shizuoka, Japan aut NATIONALLICENCE 700 1- Nakajima Takashi Pathology Division, Shizuoka Cancer Center, Shizuoka, Japan aut NATIONALLICENCE 700 1- Tsubosa Yasuhiro Division of Esophageal Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, 411-8777, Nagaizumi, Shizuoka, Japan aut NATIONALLICENCE 773 0- Esophagus Springer Japan 12/3(2015-07-01), 251-257 1612-9059 12:3<251 2015 12 10388