caa a22 4500 606204474 CHVBK 20210128101002.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s10388-014-0441-9 doi (NATIONALLICENCE)springer-10.1007/s10388-014-0441-9 Cytomegalovirus-associated ulceration of gastric conduit after chemoradiotherapy following esophagectomy for cancer [Elektronische Daten] [Yasunori Matsuda, Satoru Kishida, Hikaru Miyamoto, Shigeru Lee, Masato Okawa, Yushi Fujiwara, Ryoya Hashiba, Eijiro Edagawa, Sayaka Tanaka, Masahiko Osawa, Harushi Osugi] A 64-year-old man underwent radical esophagectomy for cancer and simultaneous reconstruction using the gastric conduit through the posterior mediastinum. Two courses of adjuvant chemotherapy were performed. Twenty-eight months postoperatively, recurrence of the cancer was detected in the mediastinal lymph nodes, and he underwent concurrent chemoradiotherapy and boost chemotherapy. Endoscopy was then performed to investigate the cause of epigastralgia, and multiple ulcerations were found in the lesser curvature of the gastric conduit. Although a proton-pump inhibitor was orally administered, the ulceration was intractable. Re-examination of the original biopsy specimens and serological testing revealed positivity for cytomegalovirus. The ulcers began to heal after administration of foscarnet sodium. After the treatment, no signs of exacerbation associated with reinstitution of chemotherapy were observed. The Author(s), 2014 Cytomegalovirus nationallicence Gastric conduit nationallicence Radical esophagectomy nationallicence Ulceration nationallicence Matsuda Yasunori Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Kishida Satoru Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Miyamoto Hikaru Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Lee Shigeru Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Okawa Masato Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Fujiwara Yushi Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Hashiba Ryoya Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Edagawa Eijiro Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Tanaka Sayaka Department of Diagnostic Pathology, Graduate School of Medicine, Osaka City University, Osaka, Japan aut Osawa Masahiko Department of Diagnostic Pathology, Graduate School of Medicine, Osaka City University, Osaka, Japan aut Osugi Harushi Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Esophagus Springer Japan 12/3(2015-07-01), 300-303 1612-9059 12:3<300 2015 12 10388 https://doi.org/10.1007/s10388-014-0441-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10388-014-0441-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Matsuda Yasunori Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 700 1- Kishida Satoru Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 700 1- Miyamoto Hikaru Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 700 1- Lee Shigeru Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 700 1- Okawa Masato Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 700 1- Fujiwara Yushi Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 700 1- Hashiba Ryoya Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 700 1- Edagawa Eijiro Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 700 1- Tanaka Sayaka Department of Diagnostic Pathology, Graduate School of Medicine, Osaka City University, Osaka, Japan aut NATIONALLICENCE 700 1- Osawa Masahiko Department of Diagnostic Pathology, Graduate School of Medicine, Osaka City University, Osaka, Japan aut NATIONALLICENCE 700 1- Osugi Harushi Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 773 0- Esophagus Springer Japan 12/3(2015-07-01), 300-303 1612-9059 12:3<300 2015 12 10388