caa a22 4500 606204555 CHVBK 20210128101003.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s10388-014-0467-z doi (NATIONALLICENCE)springer-10.1007/s10388-014-0467-z Primary adenocarcinoma in the middle thoracic esophagus, which revealed scirrhous-like growth [Elektronische Daten] [Masayuki Urabe, Kazuhiko Mori, Masato Nishida, Koichi Yagi, Yukinori Yamagata, Susumu Aikou, Hiroharu Yamashita, Sachiyo Nomura, Aya Shinozaki-Ushiku, Masashi Fukayama, Yasuyuki Seto] A 63-year-old man presented with a protruded tumor in the middle thoracic esophagus demonstrated by endoscopy. The tumor showed diffuse submucosal infiltrations, and the biopsy yielded a pathological diagnosis of adenocarcinoma. As an initial treatment, definitive chemoradiotherapy was performed. Although subsequent evaluations by endoscopy showed a good response, the lesion presented stenotic change. Positron emission tomography showed abnormally increased accumulation of 18F-fluorodeoxyglucose in the primary lesion suspicious for remnant disease. Therefore, the patient underwent salvage esophagectomy. On the resected specimen, the tumor was localized within the middle third of the esophagus: Its anal side was lined by non-cancerous squamous cell epithelium. The tumor was pathologically diagnosed as moderate to poorly differentiated adenocarcinoma. The tumor accompanied a circular stricture and a prominent fibrosis, a histologic finding known as scirrhous-type growth. Here, we report a case of scirrhous-like adenocarcinoma arising from middle thoracic esophagus successfully operated on after definitive chemoradiotherapy. The Japan Esophageal Society and Springer Japan, 2014 Esophageal neoplasms nationallicence Adenocarcinoma nationallicence Scirrhous nationallicence Middle thoracic esophagus nationallicence Urabe Masayuki Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut Mori Kazuhiko Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut Nishida Masato Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut Yagi Koichi Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut Yamagata Yukinori Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut Aikou Susumu Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut Yamashita Hiroharu Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut Nomura Sachiyo Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut Shinozaki-Ushiku Aya Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan aut Fukayama Masashi Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan aut Seto Yasuyuki Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut Esophagus Springer Japan 12/4(2015-10-01), 365-369 1612-9059 12:4<365 2015 12 10388 https://doi.org/10.1007/s10388-014-0467-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10388-014-0467-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Urabe Masayuki Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut NATIONALLICENCE 700 1- Mori Kazuhiko Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut NATIONALLICENCE 700 1- Nishida Masato Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut NATIONALLICENCE 700 1- Yagi Koichi Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut NATIONALLICENCE 700 1- Yamagata Yukinori Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut NATIONALLICENCE 700 1- Aikou Susumu Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut NATIONALLICENCE 700 1- Yamashita Hiroharu Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut NATIONALLICENCE 700 1- Nomura Sachiyo Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut NATIONALLICENCE 700 1- Shinozaki-Ushiku Aya Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Fukayama Masashi Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Seto Yasuyuki Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan aut NATIONALLICENCE 773 0- Esophagus Springer Japan 12/4(2015-10-01), 365-369 1612-9059 12:4<365 2015 12 10388