caa a22 4500 606204563 CHVBK 20210128101003.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s10388-014-0471-3 doi (NATIONALLICENCE)springer-10.1007/s10388-014-0471-3 Superficial esophageal carcinoma composed of basaloid, adenocarcinomatous, and squamous components [Elektronische Daten] [Yohei Ozawa, Fumiyoshi Fujishima, Ken Ito, Hiroshi Okamoto, Jin Teshima, Takashi Kamei, Go Miyata, Noriaki Ohuchi, Hironobu Sasano] A 60-year-old man diagnosed with esophageal cancer of the lower thoracic esophagus was referred for curative operation. Thoracoscopic esophagectomy with two-field lymph node dissection was performed without neoadjuvant therapy. Histopathological findings revealed three different components of carcinoma in the same tumor specimen: basaloid, adenocarcinomatous and squamous components. These different components of the tumor histological subtypes existed separately with clear borderline, but the histological transition among these components was partially appreciated. All of components were associated with different patterns in immunohistochemistry. The patient was well without recurrence 24months after operation. It is well known that esophageal carcinoma have histological variety and variant types of esophageal carcinoma frequently colocalized with squamous component. However, the presence of three components which occupied the same proportion of the lesion in the superficial carcinoma has not been reported to the best of our knowledge. We finally interpreted this tumor as a composite tumor arising from squamous epithelium and differentiated into three different histologic phenotypes. Because of the various morphological features of esophageal carcinoma, detailed histopathological analysis of surgical specimens plays pivotal roles in obtaining their clinicopathological features. The Japan Esophageal Society and Springer Japan, 2014 Esophageal carcinoma nationallicence Basaloid squamous carcinoma nationallicence Adenocarcinoma nationallicence Histological variety nationallicence Ozawa Yohei Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Japan aut Fujishima Fumiyoshi Department of Pathology, Tohoku University Hospital, Sendai, Japan aut Ito Ken Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Japan aut Okamoto Hiroshi Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Japan aut Teshima Jin Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Japan aut Kamei Takashi Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Japan aut Miyata Go Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Japan aut Ohuchi Noriaki Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Japan aut Sasano Hironobu Department of Pathology, Graduate School of Medicine, Tohoku University, Sendai, Japan aut Esophagus Springer Japan 12/4(2015-10-01), 370-376 1612-9059 12:4<370 2015 12 10388 https://doi.org/10.1007/s10388-014-0471-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10388-014-0471-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ozawa Yohei Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Japan aut NATIONALLICENCE 700 1- Fujishima Fumiyoshi Department of Pathology, Tohoku University Hospital, Sendai, Japan aut NATIONALLICENCE 700 1- Ito Ken Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Japan aut NATIONALLICENCE 700 1- Okamoto Hiroshi Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Japan aut NATIONALLICENCE 700 1- Teshima Jin Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Japan aut NATIONALLICENCE 700 1- Kamei Takashi Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Japan aut NATIONALLICENCE 700 1- Miyata Go Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Japan aut NATIONALLICENCE 700 1- Ohuchi Noriaki Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Japan aut NATIONALLICENCE 700 1- Sasano Hironobu Department of Pathology, Graduate School of Medicine, Tohoku University, Sendai, Japan aut NATIONALLICENCE 773 0- Esophagus Springer Japan 12/4(2015-10-01), 370-376 1612-9059 12:4<370 2015 12 10388