caa a22 4500 606204652 CHVBK 20210128101003.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s10388-014-0481-1 doi (NATIONALLICENCE)springer-10.1007/s10388-014-0481-1 Oral and pharyngeal bolus transit in gastroesophageal reflux disease [Elektronische Daten] [Rachel Cassiani, Gustavo Mota, Roberto Dantas] Background: Gastroesophageal reflux disease (GERD) is a cause of dysphagia. Our aim in this investigation was to evaluate the duration of the oral and pharyngeal transit in patients with GERD, with the hypothesis that these patients may have an alteration of oral-pharyngeal transit. Method: The swallow of 31 patients with GERD, 27 with erosive esophagitis, 15 with mild dysphagia for solid foods, and 26 controls was evaluated by the videofluoroscopic method. Controls and patients swallowed in duplicate 5 and 10mL boluses of liquid and paste consistency. Results: Transit was longer in patients with GERD than controls through the upper esophageal sphincter with 5mL liquid bolus [controls: 0.39 (0.10)s, GERD: 0.47 (0.21)s, p=0.01], through the mouth and from mouth to esophagus with 10mL liquid bolus, and through the pharynx, and upper esophageal sphincter [0.45 (0.11)s, GERD: 0.51 (0.26)s, p=0.01] with 10mL paste bolus. In patients with erosive esophagitis and dysphagia, the duration of transit through the upper esophageal sphincter was longer in patients than in controls. Such difference was not seen when the upper esophageal sphincter transit duration of patients with erosive esophagitis without dysphagia was compared with controls. There was no bolus aspiration into the airway in any subject. Pharyngeal residues were seen in the same proportion of patients and controls. Conclusion: Swallowed bolus flow through the upper esophageal sphincter of patients with GERD is slower than that seen in normal volunteers, mainly in patients with erosive disease associated with dysphagia. The Japan Esophageal Society and Springer Japan, 2014 Gastroesophageal reflux disease nationallicence Swallowing nationallicence Deglutition nationallicence Esophagitis nationallicence Upper esophageal sphincter nationallicence Deglutition disorders nationallicence Cassiani Rachel Department of Medicine, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil aut Mota Gustavo Department of Surgery, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil aut Dantas Roberto Department of Medicine, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil aut Esophagus Springer Japan 12/4(2015-10-01), 345-351 1612-9059 12:4<345 2015 12 10388 https://doi.org/10.1007/s10388-014-0481-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10388-014-0481-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cassiani Rachel Department of Medicine, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil aut NATIONALLICENCE 700 1- Mota Gustavo Department of Surgery, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil aut NATIONALLICENCE 700 1- Dantas Roberto Department of Medicine, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil aut NATIONALLICENCE 773 0- Esophagus Springer Japan 12/4(2015-10-01), 345-351 1612-9059 12:4<345 2015 12 10388