caa a22 4500 606206833 CHVBK 20210128101013.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s10353-015-0297-9 doi (NATIONALLICENCE)springer-10.1007/s10353-015-0297-9 Evolution of a surgical service for adrenal pathology and impact of surgical intervention on resistant hypertension [Elektronische Daten] [C. Lodge, A. Aghousini, R. Mannion, D. Alexander] Summary: Background: An insight into the impact of adrenalectomy on the management of hypertension is helpful in counselling patients when deciding on surgical intervention. Methods: We prospectively studied the outcome after surgical intervention for proven functional adrenal adenomas, particularly in regard to post-operative requirement of antihypertensive medications. All patients were prospectively logged onto a comprehensive database, which allowed subsequent long-term follow-up. Account was taken of morbidity encountered. Results: A total of 77 patients (78 adrenal glands) underwent adrenal surgery between 1995 and 2013. In all, 44 patients (44/77) had proven functional adenomas, phaeochromocytoma (15/44, 34 %), Conn's (25/44, 56 %), Cushing's 4 (4/44, 10 %). A minimum follow-up of 12 months revealed all patients to have a reduction in their disease-specific medication with 75 % Cushing's, 72 % Conn's and 60 % phaeochromocytoma patients medicine free. Conclusions: Despite the potential for functioning adenomas to produce irreversible change, the intervention of adrenalectomy appears to be beneficial in the vast majority of patients with at least half independent of antihypertensive medication. A reduction in morbidity was demonstrated as experience increased. Springer-Verlag Wien, 2015 Hypertension nationallicence Adrenalectomy nationallicence Conn's nationallicence Outcome nationallicence Laparoscopic nationallicence Lodge C. York District Hospital, Wigginton Road, YO31 8HE, York, Yorkshire, UK aut Aghousini A. York District Hospital, Wigginton Road, YO31 8HE, York, Yorkshire, UK aut Mannion R. York District Hospital, Wigginton Road, YO31 8HE, York, Yorkshire, UK aut Alexander D. York District Hospital, Wigginton Road, YO31 8HE, York, Yorkshire, UK aut European Surgery Springer Vienna 47/1(2015-02-01), 15-19 1682-8631 47:1<15 2015 47 10353 https://doi.org/10.1007/s10353-015-0297-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10353-015-0297-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lodge C. York District Hospital, Wigginton Road, YO31 8HE, York, Yorkshire, UK aut NATIONALLICENCE 700 1- Aghousini A. York District Hospital, Wigginton Road, YO31 8HE, York, Yorkshire, UK aut NATIONALLICENCE 700 1- Mannion R. York District Hospital, Wigginton Road, YO31 8HE, York, Yorkshire, UK aut NATIONALLICENCE 700 1- Alexander D. York District Hospital, Wigginton Road, YO31 8HE, York, Yorkshire, UK aut NATIONALLICENCE 773 0- European Surgery Springer Vienna 47/1(2015-02-01), 15-19 1682-8631 47:1<15 2015 47 10353