caa a22 4500 606206876 CHVBK 20210128101013.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s10353-015-0355-3 doi (NATIONALLICENCE)springer-10.1007/s10353-015-0355-3 The impact of advanced age on short- and long-term results after surgery for colorectal cancer [Elektronische Daten] [A. Dinnewitzer, C. Nawara, C. Augschöll, D. Neureiter, W. Hitzl, D. Öfner, T. Jäger] Summary: Background: Elderly patients with colorectal cancer are often seen as high-risk candidates for surgical treatment. This study was designed to characterize the outcomes of persons older than 80 years, compared with younger persons. Methods: We investigated the short-term surgical outcome and long-term survival of octogenarians undergoing surgery for colorectal cancer in a retrospective analysis. All patients scheduled for surgical resection of colorectal adenocarcinoma at our institution from 2003 to 2010 were included. Results: Our study included 699 patients, 126 (18 %) of whom were aged 80 years or older. Presentation with later stage disease was not seen more frequently in the octogenarians. Comorbidities showed a significant increase (p < 0.001) and more emergency operations had to be performed in the elderly (p = 0.015). The probability for postoperative complications was associated with advanced age (p = 0.009) and 1-year mortality was significantly higher in the octogenarians. Overall survival was shorter in octogenarians, but no difference was found in cancer-specific survival or time-to-recurrence, compared with patients under 80. Conclusion: Surgery for colorectal cancer in the elderly is challenging due to preexisting comorbidities and an increased rate of emergency operations. Although the short-term outcome of octogenarians is worse compared to younger patients, the long-term oncological results remain satisfactory, leading to the assumption that advanced age alone should not be a contraindication for surgical therapy. Springer-Verlag Wien, 2015 Colon cancer nationallicence Rectal cancer nationallicence Elderly patients nationallicence Octogenarians nationallicence Dinnewitzer A. Department of Surgery, Paracelsus Medical University, Müllner Hauptstrasse 48, 5020, Salzburg, Austria aut Nawara C. Department of Surgery, Paracelsus Medical University, Müllner Hauptstrasse 48, 5020, Salzburg, Austria aut Augschöll C. Department of Surgery, Paracelsus Medical University, Müllner Hauptstrasse 48, 5020, Salzburg, Austria aut Neureiter D. Institute of Pathology, Paracelsus Medical University, Salzburg, Austria aut Hitzl W. Research Office, Biostatistics, Paracelsus Medical University, Salzburg, Austria aut Öfner D. Department of Surgery, Paracelsus Medical University, Müllner Hauptstrasse 48, 5020, Salzburg, Austria aut Jäger T. Department of Surgery, Paracelsus Medical University, Müllner Hauptstrasse 48, 5020, Salzburg, Austria aut European Surgery Springer Vienna 47/6(2015-12-01), 331-336 1682-8631 47:6<331 2015 47 10353 https://doi.org/10.1007/s10353-015-0355-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10353-015-0355-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dinnewitzer A. Department of Surgery, Paracelsus Medical University, Müllner Hauptstrasse 48, 5020, Salzburg, Austria aut NATIONALLICENCE 700 1- Nawara C. Department of Surgery, Paracelsus Medical University, Müllner Hauptstrasse 48, 5020, Salzburg, Austria aut NATIONALLICENCE 700 1- Augschöll C. Department of Surgery, Paracelsus Medical University, Müllner Hauptstrasse 48, 5020, Salzburg, Austria aut NATIONALLICENCE 700 1- Neureiter D. Institute of Pathology, Paracelsus Medical University, Salzburg, Austria aut NATIONALLICENCE 700 1- Hitzl W. Research Office, Biostatistics, Paracelsus Medical University, Salzburg, Austria aut NATIONALLICENCE 700 1- Öfner D. Department of Surgery, Paracelsus Medical University, Müllner Hauptstrasse 48, 5020, Salzburg, Austria aut NATIONALLICENCE 700 1- Jäger T. Department of Surgery, Paracelsus Medical University, Müllner Hauptstrasse 48, 5020, Salzburg, Austria aut NATIONALLICENCE 773 0- European Surgery Springer Vienna 47/6(2015-12-01), 331-336 1682-8631 47:6<331 2015 47 10353