caa a22 4500 606206922 CHVBK 20210128101014.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s10353-015-0360-6 doi (NATIONALLICENCE)springer-10.1007/s10353-015-0360-6 Season and vitamin D status do not affect probability for surgical site infection after colorectal surgery [Elektronische Daten] [O.A. Turan, R. Babazade, Y. Eshraghi, J. You, A. Turan, F. Remzi] Summary: Background: Regardless of reports on the prevalence of hypovitaminosis D and seasonal effects in the general population and significant worsening of many outcomes there is a scarcity of studies focusing on surgical patients. We, therefore, designed a study to assess the association and difference in surgical-wound infections between patients having colorectal surgery in winter compared with patients having surgery in summer months. Methods: Patients were divided into winter and summer surgical procedures depending on their date of surgery. The relationship between seasons (and Vitamin D) and primary outcome of wound infections using multivariable logistic regression was assessed. Results: Out of 2919 patients, 241 (7.7 %) experience surgical site infection. The observed incidence of any surgical site infection postoperatively was 6.8 %, 9.9 %, 7.3 %, and 8.2 % for patients having surgery in spring, summer, fall, and winter, respectively. Furthermore, vitamin D concentration was not associated with incidence of surgical site infection (Odds Ratio (OR): 0.51(0.01, 27) for a one-unit increase in vitamin D concentration; p = 0.74). Conclusion: Our analysis suggests that perioperative vitamin D concentration is not associated with surgical site infections in colorectal surgical patients, likely because the outcomes are overwhelmingly determined by other baseline and surgical factors. Springer-Verlag Wien, 2015 Seasons nationallicence Vitamin D nationallicence Surgical-wound infection nationallicence Colorectal surgery nationallicence Turan O.A. Department of Colorectal Surgery, Cleveland Clinic, Cleveland, OH, USA aut Babazade R. Department of Outcomes Research, Anesthesiology Institute, Cleveland Clinic, Cleveland, OH, USA aut Eshraghi Y. Department of Pain Management, Cleveland Clinic, Cleveland, OH, USA aut You J. Departments of Quantitative Health Sciences and Outcomes Research, Cleveland Clinic, Cleveland, OH, USA aut Turan A. Department of Outcomes Research, Anesthesiology Institute, Cleveland Clinic, 9500 Euclid Avenue - P77, 44195, Cleveland, OH, USA aut Remzi F. Department of Colorectal Surgery, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH, USA aut European Surgery Springer Vienna 47/6(2015-12-01), 341-345 1682-8631 47:6<341 2015 47 10353 https://doi.org/10.1007/s10353-015-0360-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10353-015-0360-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Turan O.A. Department of Colorectal Surgery, Cleveland Clinic, Cleveland, OH, USA aut NATIONALLICENCE 700 1- Babazade R. Department of Outcomes Research, Anesthesiology Institute, Cleveland Clinic, Cleveland, OH, USA aut NATIONALLICENCE 700 1- Eshraghi Y. Department of Pain Management, Cleveland Clinic, Cleveland, OH, USA aut NATIONALLICENCE 700 1- You J. Departments of Quantitative Health Sciences and Outcomes Research, Cleveland Clinic, Cleveland, OH, USA aut NATIONALLICENCE 700 1- Turan A. Department of Outcomes Research, Anesthesiology Institute, Cleveland Clinic, 9500 Euclid Avenue - P77, 44195, Cleveland, OH, USA aut NATIONALLICENCE 700 1- Remzi F. Department of Colorectal Surgery, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH, USA aut NATIONALLICENCE 773 0- European Surgery Springer Vienna 47/6(2015-12-01), 341-345 1682-8631 47:6<341 2015 47 10353