caa a22 4500 606206981 CHVBK 20210128101014.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s10353-015-0314-z doi (NATIONALLICENCE)springer-10.1007/s10353-015-0314-z Liposarcoma with lymph node spread: a case presentation and a systematic review of the literature [Elektronische Daten] [I.B. Correia de Sá, J. Carvalho, R. Silva, P. Ferreira, L. Matos-Lima, A. Taveira-Gomes] Summary: Background: Liposarcomas are neoplasms of mesodermic origin derived from adipose tissue. Metastases at the time of initial presentation are uncommon, and the spread to regional nodes is extremely infrequent. The aim of this work is to present a rare case of a giant liposarcoma, presenting with regional lymph node extension, and composed of three different histological subtypes and present a systematic review of all the cases described in the literature of liposarcoma with lymphatic extension. Methods: A 71-year-old woman presented with a giant retroperitoneal liposarcoma with lymph node invasion. Excision of the tumor en bloc with right radical nephrectomy and lymphadenectomy was performed. Histological analysis revealed a mixed-type liposarcoma consisting of well-differentiated, myxoid, and pleomorphic components, and lymph node involvement. A systematic review of the literature of the cases of liposarcoma with lymph node involvement was performed. Results: This is the first description of a retroperitoneal liposarcoma with lymphatic involvement. There are only seven articles, including 9 patients, in literature describing lymph node invasion of liposarcomas. The majority are dedifferentiated liposarcomas. Conclusions: Giant retroperitoneal liposarcomas with mixed histological pattern and lymph node invasion are rare presentation in the literature and associated with a poor prognosis. The available data are spare, and our understanding of these tumors is limited, with no known effective therapy. Springer-Verlag Wien, 2015 Liposarcoma nationallicence Sarcoma nationallicence Lymph nationallicence Node nationallicence Metastasis nationallicence Correia de Sá I.B. Department of Plastic and Reconstructive Surgery, Hospital de S. João, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal aut Carvalho J. Department of Plastic and Reconstructive Surgery, Hospital de S. João, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal aut Silva R. Departement of Pathological Anatomy, Hospital de S. João, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal aut Ferreira P. Department of General Surgery, Hospital de S. João, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal aut Matos-Lima L. Department of General Surgery, Hospital de S. João, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal aut Taveira-Gomes A. Faculty of Medicine, University of Porto, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal aut European Surgery Springer Vienna 47/3(2015-06-01), 94-100 1682-8631 47:3<94 2015 47 10353 https://doi.org/10.1007/s10353-015-0314-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10353-015-0314-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Correia de Sá I.B. Department of Plastic and Reconstructive Surgery, Hospital de S. João, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal aut NATIONALLICENCE 700 1- Carvalho J. Department of Plastic and Reconstructive Surgery, Hospital de S. João, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal aut NATIONALLICENCE 700 1- Silva R. Departement of Pathological Anatomy, Hospital de S. João, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal aut NATIONALLICENCE 700 1- Ferreira P. Department of General Surgery, Hospital de S. João, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal aut NATIONALLICENCE 700 1- Matos-Lima L. Department of General Surgery, Hospital de S. João, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal aut NATIONALLICENCE 700 1- Taveira-Gomes A. Faculty of Medicine, University of Porto, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal aut NATIONALLICENCE 773 0- European Surgery Springer Vienna 47/3(2015-06-01), 94-100 1682-8631 47:3<94 2015 47 10353