caa a22 4500 606207341 CHVBK 20210128101016.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s10353-015-0348-2 doi (NATIONALLICENCE)springer-10.1007/s10353-015-0348-2 Outcome of anal and rectal melanoma: has site of origin a prognostic value? Analysis of 287 patients [Elektronische Daten] [A. Ciarrocchi, R. Pietroletti, F. Carlei, G. Amicucci] Summary: Introduction: To investigate the prognostic role of site of origin for primary anorectal melanoma. Methods: Data regarding patients affected by primary melanoma of the anal canal and rectum were retrieved from the surveillance, epidemiology, and end results database. Age, gender, tumor stage, tumor location, receipt of radiotherapy, and type of surgical intervention were introduced as covariates in a Cox proportional hazards regression model. Results: Our population constituted of 177 patients affected by anal canal melanoma and 110 by rectal melanoma. Tumor stage resulted to be the only independent predictor of survival (P = 0.002; hazards ratio 1.819; 95 % confidence interval 1.255-2.636). Tumor location failed to reach statistical significance. Conclusion: Site of origin of anorectal melanoma does not affect overall survival in patients undergoing surgery. Springer-Verlag Wien, 2015 Anorectal melanoma nationallicence Tumor of the rectum nationallicence Malignant melanoma nationallicence Ciarrocchi A. General and Emergency Surgery, Via Vetoio, San Salvatore Hospital, University of L'Aquila, L'Aquila, Italy aut Pietroletti R. Postgraduate school of Digestive Surgery, University of L'Aquila, L'Aquila, Italy aut Carlei F. Postgraduate school of Digestive Surgery, University of L'Aquila, L'Aquila, Italy aut Amicucci G. General and Emergency Surgery, Via Vetoio, San Salvatore Hospital, University of L'Aquila, L'Aquila, Italy aut European Surgery Springer Vienna 47/5(2015-10-01), 262-265 1682-8631 47:5<262 2015 47 10353 https://doi.org/10.1007/s10353-015-0348-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10353-015-0348-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ciarrocchi A. General and Emergency Surgery, Via Vetoio, San Salvatore Hospital, University of L'Aquila, L'Aquila, Italy aut NATIONALLICENCE 700 1- Pietroletti R. Postgraduate school of Digestive Surgery, University of L'Aquila, L'Aquila, Italy aut NATIONALLICENCE 700 1- Carlei F. Postgraduate school of Digestive Surgery, University of L'Aquila, L'Aquila, Italy aut NATIONALLICENCE 700 1- Amicucci G. General and Emergency Surgery, Via Vetoio, San Salvatore Hospital, University of L'Aquila, L'Aquila, Italy aut NATIONALLICENCE 773 0- European Surgery Springer Vienna 47/5(2015-10-01), 262-265 1682-8631 47:5<262 2015 47 10353