caa a22 4500 606211268 CHVBK 20210128101037.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s10926-014-9547-0 doi (NATIONALLICENCE)springer-10.1007/s10926-014-9547-0 Validation of the EQ-5D in Patients with Traumatic Limb Injury [Elektronische Daten] [Mei-Chuan Hung, Wen-Shian Lu, Sheng-Shiung Chen, Wen-Hsuan Hou, Ching-Lin Hsieh, Jung-Der Wang] Purpose The measurement properties of the EQ-5D have not been explored for patients with traumatic limb injuries. The purpose of this study was to examine the construct validity, predictive validity, and responsiveness of the EQ-5D in patients with traumatic limb injuries. Methods A consecutive cohort of 1,167 patients was assessed with the EQ-5D and the World Health Organization Quality of Life instrument (WHOQOL-BREF) at baseline while the patients were hospitalized because of the injury, and the patients were followed up at 3months (1,003 patients), 6months (1,010 patients), and 12months (987 patients) after injury via telephone interview. Results The utility and visual analogue scale (VAS) scores of the EQ-5D had moderate to high association with the physical and psychological domains and the two general questions (overall QOL and overall health) of the WHOQOL-BREF at all time points except baseline (Pearson's correlation coefficient >0.3), but the EQ-5D profiles were weakly associated with the social and environment domains of the WHOQOL-BREF (absolute value of Spearman's correlation coefficient <0.3). These results indicate that the EQ-5D has satisfactory construct validity. The utility and VAS scores of the EQ-5D at 3 and 6months after injury can predict (with moderate to large relationships) the four domains and two general questions of the WHOQOL-BREF administered at 12months after injury. The responsiveness of the utility and VAS of the EQ-5D were high (effect sizes >0.9) at 0-3, 0-6, and 0-12months after injury. Conclusions The EQ-5D has sufficient construct validity, predictive validity, and responsiveness, and also provides evidence for using the utility of the EQ-5D for cost-utility analyses of patients with traumatic limb injuries in the future. Springer Science+Business Media New York, 2014 EQ-5D nationallicence Traumatic limb injury nationallicence Construct validity nationallicence Predictive validity nationallicence Responsiveness nationallicence Hung Mei-Chuan Department of Public Health, National Cheng Kung University College of Medicine, Tainan, Taiwan aut Lu Wen-Shian School of Occupational Therapy, Chung Shan Medical University, Taichung, Taiwan aut Chen Sheng-Shiung Department of Physical Medicine and Rehabilitation, E-Da Hospital and I-Shou University, Kaohsiung, Taiwan aut Hou Wen-Hsuan Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, Taipei, Taiwan aut Hsieh Ching-Lin School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan aut Wang Jung-Der Department of Public Health, National Cheng Kung University College of Medicine, Tainan, Taiwan aut Journal of Occupational Rehabilitation Springer US; http://www.springer-ny.com 25/2(2015-06-01), 387-393 1053-0487 25:2<387 2015 25 10926 https://doi.org/10.1007/s10926-014-9547-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10926-014-9547-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hung Mei-Chuan Department of Public Health, National Cheng Kung University College of Medicine, Tainan, Taiwan aut NATIONALLICENCE 700 1- Lu Wen-Shian School of Occupational Therapy, Chung Shan Medical University, Taichung, Taiwan aut NATIONALLICENCE 700 1- Chen Sheng-Shiung Department of Physical Medicine and Rehabilitation, E-Da Hospital and I-Shou University, Kaohsiung, Taiwan aut NATIONALLICENCE 700 1- Hou Wen-Hsuan Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, Taipei, Taiwan aut NATIONALLICENCE 700 1- Hsieh Ching-Lin School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan aut NATIONALLICENCE 700 1- Wang Jung-Der Department of Public Health, National Cheng Kung University College of Medicine, Tainan, Taiwan aut NATIONALLICENCE 773 0- Journal of Occupational Rehabilitation Springer US; http://www.springer-ny.com 25/2(2015-06-01), 387-393 1053-0487 25:2<387 2015 25 10926