caa a22 4500 606212434 CHVBK 20210128101042.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s10295-014-1547-8 doi (NATIONALLICENCE)springer-10.1007/s10295-014-1547-8 2-Keto acids based biosynthesis pathways for renewable fuels and chemicals [Elektronische Daten] [Yohei Tashiro, Gabriel Rodriguez, Shota Atsumi] Global energy and environmental concerns have driven the development of biological chemical production from renewable sources. Biological processes using microorganisms are efficient and have been traditionally utilized to convert biomass (i.e., glucose) to useful chemicals such as amino acids. To produce desired fuels and chemicals with high yield and rate, metabolic pathways have been enhanced and expanded with metabolic engineering and synthetic biology approaches. 2-Keto acids, which are key intermediates in amino acid biosynthesis, can be converted to a wide range of chemicals. 2-Keto acid pathways were engineered in previous research efforts and these studies demonstrated that 2-keto acid pathways have high potential for novel metabolic routes with high productivity. In this review, we discuss recently developed 2-keto acid-based pathways. Society for Industrial Microbiology and Biotechnology, 2014 Metabolic engineering nationallicence 2-Keto acid nationallicence Alcohol nationallicence Aldehyde nationallicence Acid nationallicence Ester nationallicence Tashiro Yohei Department of Chemistry, University of California-Davis, Davis, CA, USA aut Rodriguez Gabriel Department of Chemistry, University of California-Davis, Davis, CA, USA aut Atsumi Shota Department of Chemistry, University of California-Davis, Davis, CA, USA aut Journal of Industrial Microbiology & Biotechnology Springer Berlin Heidelberg 42/3(2015-03-01), 361-373 1367-5435 42:3<361 2015 42 10295 https://doi.org/10.1007/s10295-014-1547-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10295-014-1547-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tashiro Yohei Department of Chemistry, University of California-Davis, Davis, CA, USA aut NATIONALLICENCE 700 1- Rodriguez Gabriel Department of Chemistry, University of California-Davis, Davis, CA, USA aut NATIONALLICENCE 700 1- Atsumi Shota Department of Chemistry, University of California-Davis, Davis, CA, USA aut NATIONALLICENCE 773 0- Journal of Industrial Microbiology & Biotechnology Springer Berlin Heidelberg 42/3(2015-03-01), 361-373 1367-5435 42:3<361 2015 42 10295