caa a22 4500 606213430 CHVBK 20210128101047.0 cr unu---uuuuu 210128e20150101xx s 000 0 eng 10.1007/s00701-014-2217-3 doi (NATIONALLICENCE)springer-10.1007/s00701-014-2217-3 Intractable occipital lobe epilepsy: clinical characteristics, surgical treatment, and a systematic review of the literature [Elektronische Daten] [Peng-Fan Yang, Yan-Zeng Jia, Qiao Lin, Zhen Mei, Zi-Qian Chen, Zhi-Yong Zheng, Hui-Jian Zhang, Jia-Sheng Pei, Jun Tian, Zhong-Hui Zhong] Purpose: We reported our experience in the surgical treatment of a relatively large cohort of patients with occipital lobe epilepsy (OLE). We also carried out a systematic review of the literature on OLE. Methods: Thirty-five consecutive patients who underwent occipital resection for epilepsy were included. Diagnoses were made following presurgical evaluations, including magnetic resonance imaging (MRI), fluorodeoxyglucose-positron emission tomography (FDG-PET), scalp video-electroencephalogram (EEG) monitoring, and intracranial EEG monitoring. At last follow-up, seizure outcome was classified using the Engel classification scheme. Results: Twenty-five of 35 patients experienced/had experienced ≥1 type of aura before the seizure. Invasive recordings were used to define the epileptogenic area in 30 of 35 patients (85.7%). All patients underwent occipital lesionectomies or topectomies. Histopathology revealed: cortical dysplasias, gliosis, dysembryoplastic neuroepithelial tumor, ganglioglioma, and tuberous sclerosis. After a mean follow-up of 44months, 25 patients (71.4%) were seizure free (Engel class I), 3 (8.6%) rarely had seizures (Engel class II), 5 (14.3%) improved more than 75% (Engel class III), and 2 (5.7%) had no significant improvement (Engel class IV). Preoperatively, 12 of 33 patients (36.4%) had visual field deficits. Postoperatively, 25 patients (75.8%) had new or aggravated visual field deficits. Conclusions: The management of OLE has been aided greatly by the availability of high-resolution diagnosis. Postoperative visual field deficits occur in a significant proportion of patients. Comprehensive intracranial EEG coverage of all occipital surfaces helps to define the epileptogenic area and preserve visual function, especially in cases of focal cortical dysplasia undetectable by MRI. Springer-Verlag Wien, 2014 Electroencephalogram nationallicence Epilepsy nationallicence Intracranial electrode nationallicence Occipital lobe nationallicence Surgery nationallicence Visual aura nationallicence Yang Peng-Fan Department of Neurosurgery, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut Jia Yan-Zeng Department of Epileptology, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut Lin Qiao Department of Epileptology, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut Mei Zhen Department of Epileptology, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut Chen Zi-Qian Department of Medical Imaging, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut Zheng Zhi-Yong Department of Pathology, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut Zhang Hui-Jian Department of Neurosurgery, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut Pei Jia-Sheng Department of Neurosurgery, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut Tian Jun Department of Neurosurgery, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut Zhong Zhong-Hui Department of Epileptology, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut Acta Neurochirurgica Springer Vienna 157/1(2015-01-01), 63-75 0001-6268 157:1<63 2015 157 701 https://doi.org/10.1007/s00701-014-2217-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-014-2217-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yang Peng-Fan Department of Neurosurgery, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut NATIONALLICENCE 700 1- Jia Yan-Zeng Department of Epileptology, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut NATIONALLICENCE 700 1- Lin Qiao Department of Epileptology, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut NATIONALLICENCE 700 1- Mei Zhen Department of Epileptology, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut NATIONALLICENCE 700 1- Chen Zi-Qian Department of Medical Imaging, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut NATIONALLICENCE 700 1- Zheng Zhi-Yong Department of Pathology, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut NATIONALLICENCE 700 1- Zhang Hui-Jian Department of Neurosurgery, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut NATIONALLICENCE 700 1- Pei Jia-Sheng Department of Neurosurgery, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut NATIONALLICENCE 700 1- Tian Jun Department of Neurosurgery, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut NATIONALLICENCE 700 1- Zhong Zhong-Hui Department of Epileptology, Fuzhou General Hospital of Nanjing Command, PLA, North Road 156, West Second Ring, 350025, Fuzhou, China aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/1(2015-01-01), 63-75 0001-6268 157:1<63 2015 157 701