caa a22 4500 606213600 CHVBK 20210128101048.0 cr unu---uuuuu 210128e20150101xx s 000 0 eng 10.1007/s00701-014-2260-0 doi (NATIONALLICENCE)springer-10.1007/s00701-014-2260-0 Admission B-type natriuretic peptide levels are associated with in-hospital cardiac events in patients with intracranial hemorrhage [Elektronische Daten] [Jae Park, Yoo Kim, Seung Kim, Gi-Byoung Nam] Background: Intracranial hemorrhage (ICH) is often associated with cardiac events. Twelve-lead electrocardiography (ECG) and transthoracic echocardiography are essential diagnostic tools for preoperative risk assessment. B-type natriuretic peptide (BNP) is a well-known predictor of cardiac outcome in various clinical settings. This study examined whether BNP levels on admission are associated with in-hospital cardiac events among ICH patients. Method: This prospective study enrolled 77 ICH patients who were admitted to this hospital for emergency neurosurgery. On admission, BNP levels, 12-lead ECG and transthoracic echocardiography were carried out for all patients. These patients were divided into two groups: Group I included 19 patients (10 men and 9 women) having 24 in-hospital cardiac events (mean age of 57 ± 15years); Group II included 57 patients (29 men, mean age of 71 ± 11years) without cardiac events. Results: Admission BNP levels of Group I patients were significantly higher than those of Group II patients (683.8 ± 1,043.8pg/ml vs 168.5 ± 173.5pg/ml, p = 0.001). In multivariate analysis, BNP levels and T-wave inversion are independent predictors of in-hospital cardiac events. A cutoff value of BNP levels (156.6pg/ml) predicted in-hospital cardiac events in ICH patients with 80% sensitivity and 66% specificity. Conclusions: Serum BNP levels and electrocardiographic T-wave inversion on admission are independent predictors of in-hospital cardiac events in patients with ICH who undergo emergency neurosurgery. Springer-Verlag Wien, 2014 BNP nationallicence Intracranial hemorrhage nationallicence In-hospital morbidity nationallicence Park Jae Department of Cardiology, Incheon-Naun Hospital, Incheon, Korea aut Kim Yoo Heart Institute, Asan Medical Center, University of Ulsan College of Medicine, 43-Gil, 88 Olympic-Ro, Seoul, Songpa-Gu, Korea aut Kim Seung Department of Neurosurgery, Kang Nam General Hospital, Yong-In, Korea aut Nam Gi-Byoung Heart Institute, Asan Medical Center, University of Ulsan College of Medicine, 43-Gil, 88 Olympic-Ro, Seoul, Songpa-Gu, Korea aut Acta Neurochirurgica Springer Vienna 157/1(2015-01-01), 21-27 0001-6268 157:1<21 2015 157 701 https://doi.org/10.1007/s00701-014-2260-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-014-2260-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Park Jae Department of Cardiology, Incheon-Naun Hospital, Incheon, Korea aut NATIONALLICENCE 700 1- Kim Yoo Heart Institute, Asan Medical Center, University of Ulsan College of Medicine, 43-Gil, 88 Olympic-Ro, Seoul, Songpa-Gu, Korea aut NATIONALLICENCE 700 1- Kim Seung Department of Neurosurgery, Kang Nam General Hospital, Yong-In, Korea aut NATIONALLICENCE 700 1- Nam Gi-Byoung Heart Institute, Asan Medical Center, University of Ulsan College of Medicine, 43-Gil, 88 Olympic-Ro, Seoul, Songpa-Gu, Korea aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/1(2015-01-01), 21-27 0001-6268 157:1<21 2015 157 701