caa a22 4500 606213651 CHVBK 20210128101048.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00701-015-2403-y doi (NATIONALLICENCE)springer-10.1007/s00701-015-2403-y Tractography of Meyer's loop for temporal lobe resection—validation by prediction of postoperative visual field outcome [Elektronische Daten] [Ylva Lilja, Maria Ljungberg, Göran Starck, Kristina Malmgren, Bertil Rydenhag, Daniel Nilsson] Background: Postoperative visual field defects are common after temporal lobe resection because of injury to the most anterior part of the optic radiation, Meyer's loop. Diffusion tensor tractography is a promising technique for visualizing the optic radiation preoperatively. The aim of this study was to assess the anatomical accuracy of Meyer's loop, visualized by the two most common tractography methods—deterministic (DTG) and probabilistic tractography (PTG)—in patients who had undergone temporal lobe resection. Methods: Eight patients with temporal lobe resection for temporal lobe pathology were included. Perimetry and diffusion tensor imaging were performed pre- and postoperatively. Two independent operators analyzed the distance between the temporal pole and Meyer's loop (TP-ML) using DTG and PTG. Results were compared to each other, to data from previously published dissection studies and to postoperative perimetry results. For the latter, Spearman's rank correlation coefficient (rs) was used. Results: Median preoperative TP-ML distances for nonoperated sides were 42 and 35mm, as determined by DTG and PTG, respectively. TP-ML assessed with PTG was a closer match to dissection studies. Intraclass correlation coefficients were 0.4 for DTG and 0.7 for PTG. Difference between preoperative TP-ML (by DTG and PTG, respectively) and resection length could predict the degree of postoperative visual field defects (DTG: rs = −0.86, p < 0.05; PTG: rs = −0.76, p < 0.05). Conclusion: Both DTG and PTG could predict the degree of visual field defects. However, PTG was superior to DTG in terms of reproducibility and anatomical accuracy. PTG is thus a strong candidate for presurgical planning of temporal lobe resection that aims to minimize injury to Meyer's loop. Springer-Verlag Wien, 2015 Diffusion tensor imaging nationallicence Meyer's loop nationallicence Optic radiation nationallicence Temporal lobe resection nationallicence Tractography nationallicence Visual field defect nationallicence Lilja Ylva Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation, The Sahlgrenska Academy at the University of Gothenburg, Per Dubbsgatan 14, 413 46, Gothenburg, Sweden aut Ljungberg Maria Department of Radiation Physics, Institute of Clinical Sciences, The Sahlgrenska Academy at the University of Gothenburg, Gula Stråket 2b, 413 45, Gothenburg, Sweden aut Starck Göran Department of Radiation Physics, Institute of Clinical Sciences, The Sahlgrenska Academy at the University of Gothenburg, Gula Stråket 2b, 413 45, Gothenburg, Sweden aut Malmgren Kristina Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation, The Sahlgrenska Academy at the University of Gothenburg, Per Dubbsgatan 14, 413 46, Gothenburg, Sweden aut Rydenhag Bertil Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation, The Sahlgrenska Academy at the University of Gothenburg, Per Dubbsgatan 14, 413 46, Gothenburg, Sweden aut Nilsson Daniel Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation, The Sahlgrenska Academy at the University of Gothenburg, Per Dubbsgatan 14, 413 46, Gothenburg, Sweden aut Acta Neurochirurgica Springer Vienna 157/6(2015-06-01), 947-956 0001-6268 157:6<947 2015 157 701 https://doi.org/10.1007/s00701-015-2403-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-015-2403-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lilja Ylva Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation, The Sahlgrenska Academy at the University of Gothenburg, Per Dubbsgatan 14, 413 46, Gothenburg, Sweden aut NATIONALLICENCE 700 1- Ljungberg Maria Department of Radiation Physics, Institute of Clinical Sciences, The Sahlgrenska Academy at the University of Gothenburg, Gula Stråket 2b, 413 45, Gothenburg, Sweden aut NATIONALLICENCE 700 1- Starck Göran Department of Radiation Physics, Institute of Clinical Sciences, The Sahlgrenska Academy at the University of Gothenburg, Gula Stråket 2b, 413 45, Gothenburg, Sweden aut NATIONALLICENCE 700 1- Malmgren Kristina Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation, The Sahlgrenska Academy at the University of Gothenburg, Per Dubbsgatan 14, 413 46, Gothenburg, Sweden aut NATIONALLICENCE 700 1- Rydenhag Bertil Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation, The Sahlgrenska Academy at the University of Gothenburg, Per Dubbsgatan 14, 413 46, Gothenburg, Sweden aut NATIONALLICENCE 700 1- Nilsson Daniel Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation, The Sahlgrenska Academy at the University of Gothenburg, Per Dubbsgatan 14, 413 46, Gothenburg, Sweden aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/6(2015-06-01), 947-956 0001-6268 157:6<947 2015 157 701