caa a22 4500 606213694 CHVBK 20210128101048.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00701-015-2411-y doi (NATIONALLICENCE)springer-10.1007/s00701-015-2411-y Feasibility of diffusion tensor tractography for preoperative prediction of the location of the facial and vestibulocochlear nerves in relation to vestibular schwannoma [Elektronische Daten] [Masanori Yoshino, Taichi Kin, Akihiro Ito, Toki Saito, Daichi Nakagawa, Kenji Ino, Kyousuke Kamada, Harushi Mori, Akira Kunimatsu, Hirofumi Nakatomi, Hiroshi Oyama, Nobuhito Saito] Background: According to recent findings, diffusion tensor tractography (DTT) only allows prediction of facial nerve location in relation to vestibular schwannoma (VS) with high probability. However, previous studies have not mentioned why only the facial nerve was selectively visualized. Our previous report investigated the optimal conditions of DTT for normal facial and vestibulocochlear nerves. In the present study, we applied the optimal conditions of DTT to VS patients to assess the feasibility of DTT for the facial and vestibulocochlear nerves. Methods: We investigated 11 patients with VS who underwent tumor resection. Visualized tracts were compared with locations of the facial and cochlear nerves as identified by intraoperative electrophysiological monitoring. Results: With the proposed method, visualized tracts corresponded to pathway area of the facial or cochlear nerves in nine of 11 patients (81.8%); specifically, to the pathway area of the facial nerve in three of 11 patients (27.3%), and to the pathway area of the cochlear nerve in six of 11 patients (54.5%). Conclusions: We visualized facial or vestibulocochlear nerves in nine of 11 patients (81.8%). For the first time, DTT proved able to visualize not only the facial nerve but also the vestibulocochlear nerve in VS patients. Despite our findings, good methods for distinguishing whether a visualized nerve tract represents facial nerve, vestibulocochlear nerve, or only noise remain unavailable. Close attention should therefore be paid to the interpretation of visualized fibers. Springer-Verlag Wien, 2015 Diffusion tensor tractography nationallicence Facial nerve nationallicence Vestibulocochlear nerve nationallicence Vestibular schwannoma nationallicence Fractional anisotropy threshold nationallicence DTT : Diffusion tensor tractography nationallicence ESE-DNAP : Elicited dorsal cochlear nucleus action potential nationallicence FA : Fractional anisotropy nationallicence ROI : Region of interest nationallicence VS : Vestibular schwannoma nationallicence Yoshino Masanori Department of Neurosurgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut Kin Taichi Department of Neurosurgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut Ito Akihiro Department of Neurosurgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut Saito Toki Departments of Clinical Information Engineering, The University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut Nakagawa Daichi Department of Neurosurgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut Ino Kenji Departments of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut Kamada Kyousuke Department of Neurosurgery, Asahikawa Medical University, 2-1 Midorigaoka-Higashi, 078-8510, Asahikawa, Hokkaido, Japan aut Mori Harushi Departments of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut Kunimatsu Akira Departments of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut Nakatomi Hirofumi Department of Neurosurgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut Oyama Hiroshi Departments of Clinical Information Engineering, The University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut Saito Nobuhito Department of Neurosurgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut Acta Neurochirurgica Springer Vienna 157/6(2015-06-01), 939-946 0001-6268 157:6<939 2015 157 701 https://doi.org/10.1007/s00701-015-2411-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-015-2411-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yoshino Masanori Department of Neurosurgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Kin Taichi Department of Neurosurgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Ito Akihiro Department of Neurosurgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Saito Toki Departments of Clinical Information Engineering, The University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Nakagawa Daichi Department of Neurosurgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Ino Kenji Departments of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Kamada Kyousuke Department of Neurosurgery, Asahikawa Medical University, 2-1 Midorigaoka-Higashi, 078-8510, Asahikawa, Hokkaido, Japan aut NATIONALLICENCE 700 1- Mori Harushi Departments of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Kunimatsu Akira Departments of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Nakatomi Hirofumi Department of Neurosurgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Oyama Hiroshi Departments of Clinical Information Engineering, The University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Saito Nobuhito Department of Neurosurgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, 113-8655, Bunkyo-ku, Tokyo, Japan aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/6(2015-06-01), 939-946 0001-6268 157:6<939 2015 157 701