caa a22 4500 606214089 CHVBK 20210128101050.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00701-015-2479-4 doi (NATIONALLICENCE)springer-10.1007/s00701-015-2479-4 Early postoperative magnet resonance tomography after resection of cerebral metastases [Elektronische Daten] [Marcel Kamp, Marion Rapp, Julia Bühner, Philipp Slotty, Dorothea Reichelt, Hosai Sadat, Maxine Dibué-Adjei, Hans-Jakob Steiger, Bernd Turowski, Michael Sabel] Background: In contrast to malignant gliomas, the impact of an early postoperative MRI after surgery of cerebral metastasis is still unclear. The present study analyses early MRI-based postoperative resection controls and incidence of in-brain progression in 116 patients suffering from 130 cerebral metastases. Methods: The extent of surgical resection was verified by an early postoperative contrast-enhanced 1.5-T MRI within 72h after surgery of cerebral metastases and correlated with in-brain progression, leptomeningeal carcinomatosis, and progression-free survival. Results: MRI confirmed complete resection was seen in 80 out of 130 metastases (61.5%). In 24 metastases (18.5%), no final decision on degree of resection could be made. Residual tumor was seen in 26 cases (20%). Local in-brain progression was observed in 40 of 130 (30.8%) cases. The incidence of in-brain progression significantly correlated with dural contact of the metastasis (p < 0.05) and residual tumor on early postoperative MRI (p < 0.0001). The odds ratio for local recurrence with residual tumor is 8.2-fold compared to no residual tumor. Conclusions: Residual tumor after metastasis extirpation was shown in nearly 20% of patients by an early postoperative MRI and significantly correlated with local in-brain progression. Furthermore, dural contact of cerebral metastases was identified as a risk factor for local recurrence. Further studies are mandatory to clearly identify the incidence of incomplete resections of cerebral metastases and their oncologic impact. An early postoperative MRI after resection of cerebral metastases is recommended as residual tumor promotes local recurrence. Springer-Verlag Wien, 2015 Postoperative MRI nationallicence Metastases nationallicence Surgery nationallicence Resection nationallicence Imaging nationallicence Kamp Marcel Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf, Germany aut Rapp Marion Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf, Germany aut Bühner Julia Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf, Germany aut Slotty Philipp Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf, Germany aut Reichelt Dorothea Institute for Diagnostic and Interventional Radiology, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany aut Sadat Hosai Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf, Germany aut Dibué-Adjei Maxine Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf, Germany aut Steiger Hans-Jakob Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf, Germany aut Turowski Bernd Institute for Diagnostic and Interventional Radiology, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany aut Sabel Michael Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf, Germany aut Acta Neurochirurgica Springer Vienna 157/9(2015-09-01), 1573-1580 0001-6268 157:9<1573 2015 157 701 https://doi.org/10.1007/s00701-015-2479-4 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-015-2479-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kamp Marcel Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf, Germany aut NATIONALLICENCE 700 1- Rapp Marion Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf, Germany aut NATIONALLICENCE 700 1- Bühner Julia Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf, Germany aut NATIONALLICENCE 700 1- Slotty Philipp Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf, Germany aut NATIONALLICENCE 700 1- Reichelt Dorothea Institute for Diagnostic and Interventional Radiology, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany aut NATIONALLICENCE 700 1- Sadat Hosai Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf, Germany aut NATIONALLICENCE 700 1- Dibué-Adjei Maxine Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf, Germany aut NATIONALLICENCE 700 1- Steiger Hans-Jakob Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf, Germany aut NATIONALLICENCE 700 1- Turowski Bernd Institute for Diagnostic and Interventional Radiology, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany aut NATIONALLICENCE 700 1- Sabel Michael Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf, Germany aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/9(2015-09-01), 1573-1580 0001-6268 157:9<1573 2015 157 701