caa a22 4500 606214143 CHVBK 20210128101051.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00701-015-2502-9 doi (NATIONALLICENCE)springer-10.1007/s00701-015-2502-9 Intracranial meningioma surgery in the elderly (over 65years): prognostic factors and outcome [Elektronische Daten] [Zhi-Yi Chen, Chuan-Hua Zheng, Tang Li,, Xiao-Yan Su, Gui-Hua Lu, Chao-Yuan Zhang, Shao-Wen Xiao, Yuan-Fu Tan] Background: Meningiomas are more prevalent in elderly individuals; however, the surgical outcome and prognostic factors in this age group are unclear. This retrospective study aimed to identify the prognostic factors of elderly patients with intracranial meningiomas who underwent surgical resection. Methods: Eighty-six patients (aged ≥65) diagnosed with an intracranial meningioma were surgically treated at our department. The clinical, radiological, and follow-up data were retrospectively reviewed. Univariate and multivariate logistic analyses were performed to identify relationships between factors [age, sex, neurological condition, concomitant disease, American Society of Anesthesiology (ASA) classification, preoperative Karnofsky Performance Scale (KPS) score, tumor location and size, peritumoral edema, and Simpson resection grade] and outcome. Results: One patient (1.2%) died within 30days of surgery. The morbidity rate was 37.2%. Postoperative morbidities occurred more frequently in the patients with preoperative neurological deficits than in those without (p = 0.049). Univariate analysis identified significant relationships between a low KPS score (≤70) at discharge and preoperative neurological deficits, low preoperative KPS score (≤70), and critical tumor location (p < 0.001, p < 0.001, and p = 0.04, respectively). In the multivariate logistic analysis, only the preoperative KPS score remained significant for the KPS score at discharge (p = 0.005); there was no significant association with the most recent KPS score. Conclusion: The outcome of intracranial meningioma resection in elderly individuals is favorable if the preoperative KPS score is >70 and no neurological deficits are present. Treatment decisions should be patient-specific, and additional factors should be considered when operations are performed in patients with a low preoperative KPS score or neurological deficits. Springer-Verlag Wien, 2015 Meningioma nationallicence Elderly nationallicence Surgery nationallicence Outcome nationallicence Prognostic factor nationallicence Chen Zhi-Yi Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, 530021, Nanning, Guangxi, China aut Zheng Chuan-Hua Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, 530021, Nanning, Guangxi, China aut Tang Li, Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, 530021, Nanning, Guangxi, China aut Su Xiao-Yan Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, 530021, Nanning, Guangxi, China aut Lu Gui-Hua Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, 530021, Nanning, Guangxi, China aut Zhang Chao-Yuan Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, 530021, Nanning, Guangxi, China aut Xiao Shao-Wen Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, 530021, Nanning, Guangxi, China aut Tan Yuan-Fu Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, 530021, Nanning, Guangxi, China aut Acta Neurochirurgica Springer Vienna 157/9(2015-09-01), 1549-1557 0001-6268 157:9<1549 2015 157 701 https://doi.org/10.1007/s00701-015-2502-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-015-2502-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chen Zhi-Yi Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, 530021, Nanning, Guangxi, China aut NATIONALLICENCE 700 1- Zheng Chuan-Hua Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, 530021, Nanning, Guangxi, China aut NATIONALLICENCE 700 1- Tang Li Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, 530021, Nanning, Guangxi, China aut NATIONALLICENCE 700 1- Su Xiao-Yan Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, 530021, Nanning, Guangxi, China aut NATIONALLICENCE 700 1- Lu Gui-Hua Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, 530021, Nanning, Guangxi, China aut NATIONALLICENCE 700 1- Zhang Chao-Yuan Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, 530021, Nanning, Guangxi, China aut NATIONALLICENCE 700 1- Xiao Shao-Wen Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, 530021, Nanning, Guangxi, China aut NATIONALLICENCE 700 1- Tan Yuan-Fu Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, 530021, Nanning, Guangxi, China aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/9(2015-09-01), 1549-1557 0001-6268 157:9<1549 2015 157 701