caa a22 4500 606214364 CHVBK 20210128101052.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s00701-015-2437-1 doi (NATIONALLICENCE)springer-10.1007/s00701-015-2437-1 Does daily tobacco smoking affect outcomes after microdecompression for degenerative central lumbar spinal stenosis? - A multicenter observational registry-based study [Elektronische Daten] [Sasha Gulati, Trond Nordseth, Ulf Nerland, Michel Gulati, Clemens Weber, Charalampis Giannadakis, Øystein Nygaard, Tore Solberg, Ole Solheim, Asgeir Jakola] Background: There are limited scientific data on the impact of smoking on patient-reported outcomes following minimally invasive spine surgery. The aim of this multicenter observational study was to examine the relationship between daily smoking and patient-reported outcome at 1 year using the Oswestry Disability Index (ODI) after microdecompression for single- and two-level central lumbar spinal stenosis (LSS). Secondary outcomes were the length of hospital stays, perioperative and postoperative complications. Method: Data were collected through the Norwegian Registry for Spine Surgery (NORspine). Results: A total of 825 patients were included (619 nonsmokers and 206 smokers). For the whole patient population there was a significant difference between preoperative ODI and ODI at 1 year (17.3 points, 95% CI 15.93-18.67, p < 0.001). There was a significant difference in ODI change at 1 year between nonsmokers and smokers (4.2 points, 95% CI 0.98-7.34, p = 0.010). At 1 year 69.6% of nonsmokers had achieved a minimal clinically important difference (≥10 points ODI improvement) compared to 60.8% of smokers (p = 0.008). There was no difference between nonsmokers and smokers in the overall complication rate (11.6% vs. 9.2%, p = 0.34). There was no difference between nonsmokers and smokers in length of hospital stays for either single-level (2.3 vs. 2.2days, p = 0.99) or two-level (3.1 vs. 2.3days, p = 0.175) microdecompression. Smoking was identified as a negative predictor for ODI change in a multiple regression analysis (p = 0.001) Conclusions: Nonsmokers experienced a significantly larger improvement at 1 year following microdecompression for LSS compared to smokers. Smokers were less likely to achieve a minimal clinically important difference. However, it should be emphasized that considerable improvement also was found among smokers. Springer-Verlag Wien, 2015 Spinal stenosis nationallicence Spondylosis nationallicence Neurosurgical procedures nationallicence Tobacco nationallicence Quality of life nationallicence Gulati Sasha Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway aut Nordseth Trond Department of Anesthesia, St. Olavs University Hospital, Trondheim, Norway aut Nerland Ulf Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway aut Gulati Michel Department of Surgery, Ålesund Hospital, Ålesund, Norway aut Weber Clemens Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway aut Giannadakis Charalampis Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway aut Nygaard Øystein Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway aut Solberg Tore Department of Neurosurgery, University Hospital of Northern Norway, Tromsø, Norway aut Solheim Ole Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway aut Jakola Asgeir Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway aut Acta Neurochirurgica Springer Vienna 157/7(2015-07-01), 1157-1164 0001-6268 157:7<1157 2015 157 701 https://doi.org/10.1007/s00701-015-2437-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-015-2437-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gulati Sasha Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway aut NATIONALLICENCE 700 1- Nordseth Trond Department of Anesthesia, St. Olavs University Hospital, Trondheim, Norway aut NATIONALLICENCE 700 1- Nerland Ulf Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway aut NATIONALLICENCE 700 1- Gulati Michel Department of Surgery, Ålesund Hospital, Ålesund, Norway aut NATIONALLICENCE 700 1- Weber Clemens Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway aut NATIONALLICENCE 700 1- Giannadakis Charalampis Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway aut NATIONALLICENCE 700 1- Nygaard Øystein Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway aut NATIONALLICENCE 700 1- Solberg Tore Department of Neurosurgery, University Hospital of Northern Norway, Tromsø, Norway aut NATIONALLICENCE 700 1- Solheim Ole Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway aut NATIONALLICENCE 700 1- Jakola Asgeir Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/7(2015-07-01), 1157-1164 0001-6268 157:7<1157 2015 157 701