caa a22 4500 606214372 CHVBK 20210128101052.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s00701-015-2440-6 doi (NATIONALLICENCE)springer-10.1007/s00701-015-2440-6 Oculomotor nerve palsy induced by internal carotid artery aneurysm: prognostic factors for recovery [Elektronische Daten] [Julien Engelhardt, Jérôme Berge, Emmanuel Cuny, Guillaume Penchet] Background: Aneurysms at the posterior face of the internal carotid artery can lead to oculomotor nerve palsy (ONP) with an uncertain prognosis of recovery post-treatment. The aim of this study was to define the prognostic factors for ONP recovery, with particular interest in treatment modality (surgery or endovascular techniques). Method: A literature review was performed to select the most pertinent prognostic factors. A retrospective study was then performed to determine whether these factors had significantly modified the prognosis of ONP recovery in our series of patients. Results: In the literature, factors linked to poorer outcome were age, vascular risk factors, initial ONP severity and delay before treatment; better recovery was associated with surgical treatment. Between 2000 and 2013, 23 consecutive patients were treated in our department for ONP-inducing aneurysms: 14 by endovascular embolization and 9 by surgical clipping and aneurysm puncture. Mean follow-up was 48.8months. After treatment, overall recovery occurred in 87% of cases, always within 6months. Apart from treatment modality, no selected prognostic factor significantly modified the quality or timing of ONP recovery. In the endovascular group, four patients recovered completely, seven partially and three did not recover. In the surgical group, seven patients recovered completely and two partially. Surgery was significantly associated with a more complete and earlier ONP recovery (p < 0.05). Conclusions: Surgery was associated with a more complete and earlier ONP recovery as compared to endovascular treatment, confirming the results of previous studies. However, conclusions must be confirmed by a prospective randomized study. Springer-Verlag Wien, 2015 Aneurysm nationallicence Internal carotid artery nationallicence Oculomotor nerve palsy nationallicence Prognosis nationallicence Recovery nationallicence Subarachnoid hemorrhage nationallicence Treatment nationallicence Engelhardt Julien CHU Pellegrin, Service de Neurochirurgie B, Hôpital Pellegrin-Tripode, Place Amélie Raba-Léon, 33 076, Bordeaux Cedex, France aut Berge Jérôme CHU Pellegrin, Service de Neuroimagerie Diagnostique et Thérapeutique, Bordeaux, France aut Cuny Emmanuel CHU Pellegrin, Service de Neurochirurgie B, Hôpital Pellegrin-Tripode, Place Amélie Raba-Léon, 33 076, Bordeaux Cedex, France aut Penchet Guillaume CHU Pellegrin, Service de Neurochirurgie B, Hôpital Pellegrin-Tripode, Place Amélie Raba-Léon, 33 076, Bordeaux Cedex, France aut Acta Neurochirurgica Springer Vienna 157/7(2015-07-01), 1103-1111 0001-6268 157:7<1103 2015 157 701 https://doi.org/10.1007/s00701-015-2440-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-015-2440-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Engelhardt Julien CHU Pellegrin, Service de Neurochirurgie B, Hôpital Pellegrin-Tripode, Place Amélie Raba-Léon, 33 076, Bordeaux Cedex, France aut NATIONALLICENCE 700 1- Berge Jérôme CHU Pellegrin, Service de Neuroimagerie Diagnostique et Thérapeutique, Bordeaux, France aut NATIONALLICENCE 700 1- Cuny Emmanuel CHU Pellegrin, Service de Neurochirurgie B, Hôpital Pellegrin-Tripode, Place Amélie Raba-Léon, 33 076, Bordeaux Cedex, France aut NATIONALLICENCE 700 1- Penchet Guillaume CHU Pellegrin, Service de Neurochirurgie B, Hôpital Pellegrin-Tripode, Place Amélie Raba-Léon, 33 076, Bordeaux Cedex, France aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/7(2015-07-01), 1103-1111 0001-6268 157:7<1103 2015 157 701