caa a22 4500 606214860 CHVBK 20210128101056.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s00701-014-2263-x doi (NATIONALLICENCE)springer-10.1007/s00701-014-2263-x AlloDerm for duraplasty in Chiari malformation: superior outcomes [Elektronische Daten] [Christian Bowers, Cameron Brimley, Chad Cole, Wayne Gluf, Richard Schmidt] Background: Autologous pericranium, fascia lata(either as autograft or allograft), bovine pericardium (DuraGuard), fetal bovine tissue (Durepair), processed collagen matrix (DuraGen), and synthetic fabrics (e.g., synthetic Goretex graft) have all been used for duraplasty in Chiari decompression surgery, and no consensus exists as to the optimal material. We reviewed our experience to compare the incidence of graft-related complications associated with using acellular human dermis allograft (AlloDerm) with those of DuraGuard, DuraGen, and Durepair. Methods: In a retrospective cohort chart review, our cohort included 119 patients who underwent 128 Chiari decompression procedures by a single surgeon from January 1, 1997, through July 31, 2012. Age, sex, smoking status, weight, and the type of dural graft used were analyzed with univariate statistical tests. Dural grafts were selected based on the commercial products available at the time of surgery during this 15-year period. Results: The reoperation rate for cerebrospinal fluid leak causing pseudomeningocele was 2.2% (1/46 cases) with the AlloDerm graft and 17.1% (14/82 cases) with other materials (p = 0.01). Each of the non-AlloDerm grafts had a higher reoperation rate than AlloDerm when analyzed separately. Not using AlloDerm was the only statistically significant factor for the need for reoperation (p = 0.01). Conclusions: The use of the AlloDerm dural graft for duraplasty in Chiari decompressions resulted in a significantly lower pseudomeningocele formation than the use of any other type of dural graft. There was no association between patient age, sex, extra weight, or smoking status and the need for reoperation. Springer-Verlag Wien, 2014 AlloDerm nationallicence Chiari decompression nationallicence Duraplasty nationallicence Dural grafts nationallicence Bowers Christian Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, 175 N. Medical Drive East, 84132, Salt Lake City, UT, USA aut Brimley Cameron University of Utah School of Medicine, Salt Lake City, UT, USA aut Cole Chad Southern Utah Neurosciences Institute, St. George, UT, USA aut Gluf Wayne Department of Neurosurgery, University of Texas Southwestern, Dallas, TX, USA aut Schmidt Richard Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, 175 N. Medical Drive East, 84132, Salt Lake City, UT, USA aut Acta Neurochirurgica Springer Vienna 157/3(2015-03-01), 507-511 0001-6268 157:3<507 2015 157 701 https://doi.org/10.1007/s00701-014-2263-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-014-2263-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bowers Christian Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, 175 N. Medical Drive East, 84132, Salt Lake City, UT, USA aut NATIONALLICENCE 700 1- Brimley Cameron University of Utah School of Medicine, Salt Lake City, UT, USA aut NATIONALLICENCE 700 1- Cole Chad Southern Utah Neurosciences Institute, St. George, UT, USA aut NATIONALLICENCE 700 1- Gluf Wayne Department of Neurosurgery, University of Texas Southwestern, Dallas, TX, USA aut NATIONALLICENCE 700 1- Schmidt Richard Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, 175 N. Medical Drive East, 84132, Salt Lake City, UT, USA aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/3(2015-03-01), 507-511 0001-6268 157:3<507 2015 157 701