caa a22 4500 606214976 CHVBK 20210128101056.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s00701-014-2292-5 doi (NATIONALLICENCE)springer-10.1007/s00701-014-2292-5 Quantifying unruptured giant intracranial aneurysms by measuring diameter and volume—a comparative analysis of 69 cases [Elektronische Daten] [Julius Dengler, Nicolai Maldaner, Philippe Bijlenga, Jan-Karl Burkhardt, Alexander Graewe, Susanne Guhl, Makoto Nakamura, Christian Hohaus, Adisa Kursumovic, Nils Schmidt, Karl-Michael Schebesch, Maria Wostrack, Peter Vajkoczy, Dorothee Mielke] Background: Intracranial aneurysms (IA) are usually quantified according to their largest diameter. However, volumetry has recently been increasingly conducted as well, especially in giant intracranial aneurysms (GIAs). Since so far the true value of GIA volumetry is unknown, we designed a trial to examine correlations between GIA diameter and volume with special focus on clinical implications. Methods: Magnetic resonance imaging of 69 unruptured GIAs in 66 patients was retrospectively evaluated. The largest diameter and volume were measured. Also, potential associations to the patients' clinical conditions were examined. Results: Comparing GIA sizes of our patient cohort produced different results depending on whether GIA diameter or volume was measured. Measuring the diameter identified posterior circulation GIAs as the largest ones (39.2mm, IQR 37.3-48.3), while measuring the volume found GIAs of the MCA to be the largest ones (12.3cm3, IQR 7.2-27.8). A correlation of GIA diameter and volume was only found in anterior circulation GIAs, which were predominantly saccular in shape, but not in those of the posterior circulation, of which most were fusiform. Neither GIA diameter nor GIA volume but only GIA location was associated with neurological deficits. Conclusion: Diameter and volume measurements are not interchangeable modes of GIA quantification. Our data suggest that the idea of distinguishing different sizes of GIA may be clinically less relevant than examining their location, shape or mass effect. Springer-Verlag Wien, 2014 Giant intracranial aneurysm nationallicence Aneurysm volume nationallicence Aneurysm diameter nationallicence Dengler Julius Department of Neurosurgery, Charité-Universitaetsmedizin Berlin, Campus Virchow Klinikum (CVK), Augustenburger Platz 1, 13353, Berlin, Germany aut Maldaner Nicolai Department of Neurosurgery, Charité-Universitaetsmedizin Berlin, Campus Virchow Klinikum (CVK), Augustenburger Platz 1, 13353, Berlin, Germany aut Bijlenga Philippe Service de Neurochirurgie, Faculté de Médecine de Genève and Hôpitaux Universitaire de Genève, Geneva, Switzerland aut Burkhardt Jan-Karl Department of Neurosurgery, University Hospital of Zurich, Zurich, Switzerland aut Graewe Alexander Department of Neurosurgery, Unfallkrankenhaus Berlin, Berlin, Germany aut Guhl Susanne Department of Neurosurgery, University of Greifswald, Greifswald, Germany aut Nakamura Makoto Department of Neurosurgery, Hannover Medical School, Hannover, Germany aut Hohaus Christian Department of Neurosurgery, BG Hospital Bergmannstrost, Halle, Germany aut Kursumovic Adisa Department of Neurosurgery and Interventional Neuroradiology, Donau-Isar-Klinikum Deggendorf, Deggendorf, Germany aut Schmidt Nils Department of Neurosurgery, University Medical Center, Hamburg Eppendorf, Hamburg, Germany aut Schebesch Karl-Michael Department of Neurosurgery, University of Regensburg, Regensburg, Germany aut Wostrack Maria Department of Neurosurgery, Technical University of Munich, Munich, Germany aut Vajkoczy Peter Department of Neurosurgery, Charité-Universitaetsmedizin Berlin, Campus Virchow Klinikum (CVK), Augustenburger Platz 1, 13353, Berlin, Germany aut Mielke Dorothee Department of Neurosurgery, Georg August University Goettingen, Goettingen, Germany aut Acta Neurochirurgica Springer Vienna 157/3(2015-03-01), 361-368 0001-6268 157:3<361 2015 157 701 https://doi.org/10.1007/s00701-014-2292-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-014-2292-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dengler Julius Department of Neurosurgery, Charité-Universitaetsmedizin Berlin, Campus Virchow Klinikum (CVK), Augustenburger Platz 1, 13353, Berlin, Germany aut NATIONALLICENCE 700 1- Maldaner Nicolai Department of Neurosurgery, Charité-Universitaetsmedizin Berlin, Campus Virchow Klinikum (CVK), Augustenburger Platz 1, 13353, Berlin, Germany aut NATIONALLICENCE 700 1- Bijlenga Philippe Service de Neurochirurgie, Faculté de Médecine de Genève and Hôpitaux Universitaire de Genève, Geneva, Switzerland aut NATIONALLICENCE 700 1- Burkhardt Jan-Karl Department of Neurosurgery, University Hospital of Zurich, Zurich, Switzerland aut NATIONALLICENCE 700 1- Graewe Alexander Department of Neurosurgery, Unfallkrankenhaus Berlin, Berlin, Germany aut NATIONALLICENCE 700 1- Guhl Susanne Department of Neurosurgery, University of Greifswald, Greifswald, Germany aut NATIONALLICENCE 700 1- Nakamura Makoto Department of Neurosurgery, Hannover Medical School, Hannover, Germany aut NATIONALLICENCE 700 1- Hohaus Christian Department of Neurosurgery, BG Hospital Bergmannstrost, Halle, Germany aut NATIONALLICENCE 700 1- Kursumovic Adisa Department of Neurosurgery and Interventional Neuroradiology, Donau-Isar-Klinikum Deggendorf, Deggendorf, Germany aut NATIONALLICENCE 700 1- Schmidt Nils Department of Neurosurgery, University Medical Center, Hamburg Eppendorf, Hamburg, Germany aut NATIONALLICENCE 700 1- Schebesch Karl-Michael Department of Neurosurgery, University of Regensburg, Regensburg, Germany aut NATIONALLICENCE 700 1- Wostrack Maria Department of Neurosurgery, Technical University of Munich, Munich, Germany aut NATIONALLICENCE 700 1- Vajkoczy Peter Department of Neurosurgery, Charité-Universitaetsmedizin Berlin, Campus Virchow Klinikum (CVK), Augustenburger Platz 1, 13353, Berlin, Germany aut NATIONALLICENCE 700 1- Mielke Dorothee Department of Neurosurgery, Georg August University Goettingen, Goettingen, Germany aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/3(2015-03-01), 361-368 0001-6268 157:3<361 2015 157 701