caa a22 4500 606215158 CHVBK 20210128101057.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s00701-015-2540-3 doi (NATIONALLICENCE)springer-10.1007/s00701-015-2540-3 Intraparenchymal ventricular diverticula in chronic obstructive hydrocephalus: prevalence, imaging features and evolution [Elektronische Daten] [Renzo Manara, Valentina Citton, Annalisa Traverso, Maria Zanotti, Roberto Faggin, Stefano Sartori, Riccardo Perini, Laura Milanese, Chiara Briani, Francesco Bona, Giuseppe Rolma, Marta Rossetto, Fabio Zerbo, Francesco Di Salle, Domenico d'Avella] Background: Intraparenchymal cavities communicating with the ventricles may appear in patients with chronic obstructive hydrocephalus despite no identifiable surgerical, vascular or traumatic causes. The rate, features, pathogenesis, evolution and clinical impact of intraparenchymal diverticula have not been outlined, yet. Methods: Brain MRIs of 130 patients (mean age: 11.3years; age range: 0-67; 60 females) with chronic obstructive hydrocephalus were analyzed. The pathogenesis, neurosurgical treatment, ventricle size, signs of transependymal reabsorption and septum pellucidum integrity of the hydrocephalus were recorded. Subarachnoid outpouching of the ventricles, post-hemorrhagic parenchymal cavities, paths of ventricular shunting and cavities not communicating with the ventricles were excluded. Of patients with intraparenchymal diverticula, all previous available CT and MRI scans were evaluated. Results: Eight patients (6.2%, mean age: 18.7years; age range: 2-42) harbored 11 intraparenchymal diverticula sprouting from the temporal (6), occipital (3) or frontal (2) horns of the lateral ventricles. Intraparenchymal diverticula were more frequent in males (p = 0.04) and older patients (18.7 ± 12.7 vs 11.3 ± 9.8years, p = 0.04). Their presence or evolution (mean neuroradiological follow-up 3.6years; range: 0-8) showed a trend of association with hydrocephalus severity (bifrontal index) and did not correlate with the surgical treatment. In three patients the diverticula progressed during follow-up. One patient presented with hemiparesis consistent with the intraparenchymal lesion and improved after ventricular shunting. A DTI study revealed that the cortico-spinal tract was partly included in the septum between the ventricle and the intraparenchymal diverticulum. Conclusions: Clinicians dealing with chronic severe obstructive hydrocephalus should be aware of ventricular intraparenchymal diverticulation. Studies aiming at clarifying their pathogenesis and proper management are warranted. Springer-Verlag Wien, 2015 DTI nationallicence Hydrocephalus nationallicence MRI nationallicence Ventricular diverticulum nationallicence Manara Renzo Neuroradiology, University of Salerno, Via S. Allende, 84081, Baronissi, SA, Italy aut Citton Valentina IRCCS S. Camillo, via Alberoni 70, 30011, Lido di Venezia, Italy aut Traverso Annalisa Department of Pediatrics, University of Padua, via Giustiniani 1, 35138, Padua, Italy aut Zanotti Maria Neuroradiology, University Hospital of Padua, via Giustiniani 1, 35138, Padua, Italy aut Faggin Roberto Neurosurgery, University Hospital of Padua, via Giustiniani 1, 35138, Padua, Italy aut Sartori Stefano Department of Pediatrics, University of Padua, via Giustiniani 1, 35138, Padua, Italy aut Perini Riccardo Neurosurgery, University Hospital of Padua, via Giustiniani 1, 35138, Padua, Italy aut Milanese Laura Department of Neuroscience, University of Padua, via Giustiniani 1, 35138, Padua, Italy aut Briani Chiara Neurology, University of Padua, via Giustiniani 1, 35138, Padua, Italy aut Bona Francesco Neuroradiology, University Hospital of Padua, via Giustiniani 1, 35138, Padua, Italy aut Rolma Giuseppe Neuroradiology, University Hospital of Padua, via Giustiniani 1, 35138, Padua, Italy aut Rossetto Marta Neurosurgery, University Hospital of Padua, via Giustiniani 1, 35138, Padua, Italy aut Zerbo Fabio Radiology, Ospedale S. Bassiano, via dei Lotti 40, 36061, Bassano del Grappa, VI, Italy aut Di Salle Francesco Neuroradiology, University of Salerno, Via S. Allende, 84081, Baronissi, SA, Italy aut d'Avella Domenico Department of Neuroscience, University of Padua, via Giustiniani 1, 35138, Padua, Italy aut Acta Neurochirurgica Springer Vienna 157/10(2015-10-01), 1721-1730 0001-6268 157:10<1721 2015 157 701 https://doi.org/10.1007/s00701-015-2540-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-015-2540-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Manara Renzo Neuroradiology, University of Salerno, Via S. Allende, 84081, Baronissi, SA, Italy aut NATIONALLICENCE 700 1- Citton Valentina IRCCS S. Camillo, via Alberoni 70, 30011, Lido di Venezia, Italy aut NATIONALLICENCE 700 1- Traverso Annalisa Department of Pediatrics, University of Padua, via Giustiniani 1, 35138, Padua, Italy aut NATIONALLICENCE 700 1- Zanotti Maria Neuroradiology, University Hospital of Padua, via Giustiniani 1, 35138, Padua, Italy aut NATIONALLICENCE 700 1- Faggin Roberto Neurosurgery, University Hospital of Padua, via Giustiniani 1, 35138, Padua, Italy aut NATIONALLICENCE 700 1- Sartori Stefano Department of Pediatrics, University of Padua, via Giustiniani 1, 35138, Padua, Italy aut NATIONALLICENCE 700 1- Perini Riccardo Neurosurgery, University Hospital of Padua, via Giustiniani 1, 35138, Padua, Italy aut NATIONALLICENCE 700 1- Milanese Laura Department of Neuroscience, University of Padua, via Giustiniani 1, 35138, Padua, Italy aut NATIONALLICENCE 700 1- Briani Chiara Neurology, University of Padua, via Giustiniani 1, 35138, Padua, Italy aut NATIONALLICENCE 700 1- Bona Francesco Neuroradiology, University Hospital of Padua, via Giustiniani 1, 35138, Padua, Italy aut NATIONALLICENCE 700 1- Rolma Giuseppe Neuroradiology, University Hospital of Padua, via Giustiniani 1, 35138, Padua, Italy aut NATIONALLICENCE 700 1- Rossetto Marta Neurosurgery, University Hospital of Padua, via Giustiniani 1, 35138, Padua, Italy aut NATIONALLICENCE 700 1- Zerbo Fabio Radiology, Ospedale S. Bassiano, via dei Lotti 40, 36061, Bassano del Grappa, VI, Italy aut NATIONALLICENCE 700 1- Di Salle Francesco Neuroradiology, University of Salerno, Via S. Allende, 84081, Baronissi, SA, Italy aut NATIONALLICENCE 700 1- d'Avella Domenico Department of Neuroscience, University of Padua, via Giustiniani 1, 35138, Padua, Italy aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/10(2015-10-01), 1721-1730 0001-6268 157:10<1721 2015 157 701