caa a22 4500 606215689 CHVBK 20210128101100.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s00701-015-2352-5 doi (NATIONALLICENCE)springer-10.1007/s00701-015-2352-5 Epidural spinal cord stimulation for neuropathic pain: a neurosurgical multicentric Italian data collection and analysis [Elektronische Daten] [Elena Colombo, Carlo Mandelli, Pietro Mortini, Giuseppe Messina, Nicola De Marco, Roberto Donati, Claudio Irace, Andrea Landi, Angelo Lavano, Massimo Mearini, Stefano Podetta, Domenico Servello, Edvin Zekaj, Carlo Valtulina, Ivano Dones] Background: Spinal cord stimulation (SCS) is a technique used worldwide to treat several types of chronic neuropathic pain refractory to any conservative treatment. The aim of this data collection is to enforce evidence of SCS effectiveness on neuropathic chronic pain reported in the literature and to speculate on the usefulness of the trial period in determining the long-term efficacy. Moreover, the very low percentage of undesired side effects and complications reported in our case series suggests that all implants should be performed by similarly well-trained and experienced professionals. Method: A multicentric data collection on a common database from 11 Italian neurosurgical departments started 3 years ago. Two different types of electrodes (paddle or percutaneous leads) were used. Of 122 patients, 73% (N = 89) were submitted to a trial period, while the remaining patients underwent the immediate permanent implant (N = 33). Statistical comparisons of continuous variables between groups were performed. Results: Most of the patients (80%) had predominant pain to their lower limbs, while only 17% of patients had prevalent axial pain. Significant reduction in pain, as measured by variation in visual analogue scale (VAS) score, was observed at least 1year after implantation in 63.8% of the cases, 59.5% of patients who underwent a test trial and 71.4% of patients who underwent permanent implant at once. No statistical differences were found between the lower-limb pain group and the axial pain group. Conclusions: No relevant differences in long-term outcomes were observed in previously tested patients compared with patients implanted at once. Through this analysis we hope to recruit new centres, to give more scientific value to our results. Springer-Verlag Wien, 2015 Spinal cord stimulation nationallicence Chronic pain nationallicence Neuropathic pain nationallicence Failed back surgery syndrome nationallicence Colombo Elena Department of Neurosurgery, IRCCS San Raffaele Hospital, Via Olgettina 60 Segrate, Milan, Italy aut Mandelli Carlo Department of Neurosurgery, IRCCS San Raffaele Hospital, Via Olgettina 60 Segrate, Milan, Italy aut Mortini Pietro Department of Neurosurgery, IRCCS San Raffaele Hospital, Via Olgettina 60 Segrate, Milan, Italy aut Messina Giuseppe Department of Neurosurgery, IRCCS C. Besta Neurological Foundation, Milan, Italy aut De Marco Nicola Department of Neurosurgery, Valtellina and Valchiavenna Hospital, Sondalo, Italy aut Donati Roberto Department of Neurosurgery, Papa Giovanni XXIII Hospital, Bergamo, Italy aut Irace Claudio Department of Neurosurgery, IGEA Clinic, Milan, Italy aut Landi Andrea Department of Neurosurgery, San Gerardo Hospital, Monza, Italy aut Lavano Angelo Department of Neurosurgery, Campanella Foundation, Catanzaro, Italy aut Mearini Massimo Department of Neurosurgery, Spedali Civili Hospital, Brescia, Italy aut Podetta Stefano Department of Neurosurgery, Poliambulanza Foundation, Brescia, Italy aut Servello Domenico Department of Neurosurgery, IRCCS Galeazzi Hospital, Milan, Italy aut Zekaj Edvin Department of Neurosurgery, IRCCS Galeazzi Hospital, Milan, Italy aut Valtulina Carlo Department of Neurosurgery, Istituti Ospitalieri Hospital, Cremona, Italy aut Dones Ivano Department of Neurosurgery, IRCCS C. Besta Neurological Foundation, Milan, Italy aut Acta Neurochirurgica Springer Vienna 157/4(2015-04-01), 711-720 0001-6268 157:4<711 2015 157 701 https://doi.org/10.1007/s00701-015-2352-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-015-2352-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Colombo Elena Department of Neurosurgery, IRCCS San Raffaele Hospital, Via Olgettina 60 Segrate, Milan, Italy aut NATIONALLICENCE 700 1- Mandelli Carlo Department of Neurosurgery, IRCCS San Raffaele Hospital, Via Olgettina 60 Segrate, Milan, Italy aut NATIONALLICENCE 700 1- Mortini Pietro Department of Neurosurgery, IRCCS San Raffaele Hospital, Via Olgettina 60 Segrate, Milan, Italy aut NATIONALLICENCE 700 1- Messina Giuseppe Department of Neurosurgery, IRCCS C. Besta Neurological Foundation, Milan, Italy aut NATIONALLICENCE 700 1- De Marco Nicola Department of Neurosurgery, Valtellina and Valchiavenna Hospital, Sondalo, Italy aut NATIONALLICENCE 700 1- Donati Roberto Department of Neurosurgery, Papa Giovanni XXIII Hospital, Bergamo, Italy aut NATIONALLICENCE 700 1- Irace Claudio Department of Neurosurgery, IGEA Clinic, Milan, Italy aut NATIONALLICENCE 700 1- Landi Andrea Department of Neurosurgery, San Gerardo Hospital, Monza, Italy aut NATIONALLICENCE 700 1- Lavano Angelo Department of Neurosurgery, Campanella Foundation, Catanzaro, Italy aut NATIONALLICENCE 700 1- Mearini Massimo Department of Neurosurgery, Spedali Civili Hospital, Brescia, Italy aut NATIONALLICENCE 700 1- Podetta Stefano Department of Neurosurgery, Poliambulanza Foundation, Brescia, Italy aut NATIONALLICENCE 700 1- Servello Domenico Department of Neurosurgery, IRCCS Galeazzi Hospital, Milan, Italy aut NATIONALLICENCE 700 1- Zekaj Edvin Department of Neurosurgery, IRCCS Galeazzi Hospital, Milan, Italy aut NATIONALLICENCE 700 1- Valtulina Carlo Department of Neurosurgery, Istituti Ospitalieri Hospital, Cremona, Italy aut NATIONALLICENCE 700 1- Dones Ivano Department of Neurosurgery, IRCCS C. Besta Neurological Foundation, Milan, Italy aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/4(2015-04-01), 711-720 0001-6268 157:4<711 2015 157 701