caa a22 4500 606216448 CHVBK 20210128101103.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s00701-014-2295-2 doi (NATIONALLICENCE)springer-10.1007/s00701-014-2295-2 The lack of relationship between intracranial pressure and cerebral ventricle indices based on brain computed tomography in patients undergoing ventriculoperitoneal shunt [Elektronische Daten] [Eugene Kim, Young-Jin Lim, Han-Seul Park, Sung-Kwon Kim, Young-Tae Jeon, Jeong-Won Hwang, Yun-Seok Lee, Hee-Pyoung Park] Background: In this study we investigated whether cerebral ventricle indices based on brain computed tomography (CT) scans are reliable for predicting intracranial pressure (ICP) in hydrocephalic patients. Methods: Electronic medical records of 221 patients undergoing ventriculoperitoneal shunt due to hydrocephalus were retrospectively reviewed. Cerebral ventricle indices including Evans' index, third ventricle index, cella media index, and ventricular score were calculated from transverse diameters measured at various levels on preoperative brain CT scans. ICP was considered as CSF opening pressure. Patients were categorized into three groups: communicating hydrocephalus, non-communicating hydrocephalus, and normal pressure hydrocephalus (NPH). The non-communicating hydrocephalus group was further divided according to the obstruction site; aqueduct, fourth ventricle outlet, third ventricle, and the foramen of Monro. The primary endpoint was the extent of the correlation between cerebral ventricle indices and ICP in each hydrocephalus group. Results: No cerebral ventricle index correlated with ICP in patients with communicating hydrocephalus (n = 113) and NPH (n = 62). In the non-communicating hydrocephalus group (n = 46), only the third ventricle index revealed moderate negative correlation with ICP (r = −0.395, p < 0.01). In subgroup analyses, the third ventricle index showed a strong negative relationship with ICP only in patients with the third ventricle obstruction (r = −0.779, p < 0.05). Conclusions: In this study we showed that although an inverse correlation existed between ICP and the third ventricle index only in patients with non-communicating hydrocephalus due to obstruction of the third ventricle, cerebral ventricle indices based on brain CT scan were non-reliable predictors of ICP in hydrocephalic patients. Springer-Verlag Wien, 2014 Cerebral ventricles nationallicence Intracranial pressure nationallicence Hydrocephalus nationallicence Ventriculoperitoneal shunt nationallicence Kim Eugene Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, 110-744, Seoul, Jongno-gu, South Korea aut Lim Young-Jin Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, 110-744, Seoul, Jongno-gu, South Korea aut Park Han-Seul Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, 110-744, Seoul, Jongno-gu, South Korea aut Kim Sung-Kwon Department of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Seoul, Jongno-gu, South Korea aut Jeon Young-Tae Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea aut Hwang Jeong-Won Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea aut Lee Yun-Seok Department of Anesthesiology and Pain Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, South Korea aut Park Hee-Pyoung Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, 110-744, Seoul, Jongno-gu, South Korea aut Acta Neurochirurgica Springer Vienna 157/2(2015-02-01), 257-263 0001-6268 157:2<257 2015 157 701 https://doi.org/10.1007/s00701-014-2295-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-014-2295-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kim Eugene Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, 110-744, Seoul, Jongno-gu, South Korea aut NATIONALLICENCE 700 1- Lim Young-Jin Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, 110-744, Seoul, Jongno-gu, South Korea aut NATIONALLICENCE 700 1- Park Han-Seul Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, 110-744, Seoul, Jongno-gu, South Korea aut NATIONALLICENCE 700 1- Kim Sung-Kwon Department of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Seoul, Jongno-gu, South Korea aut NATIONALLICENCE 700 1- Jeon Young-Tae Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea aut NATIONALLICENCE 700 1- Hwang Jeong-Won Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea aut NATIONALLICENCE 700 1- Lee Yun-Seok Department of Anesthesiology and Pain Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, South Korea aut NATIONALLICENCE 700 1- Park Hee-Pyoung Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, 110-744, Seoul, Jongno-gu, South Korea aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/2(2015-02-01), 257-263 0001-6268 157:2<257 2015 157 701