caa a22 4500 606216553 CHVBK 20210128101104.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s00701-014-2299-y doi (NATIONALLICENCE)springer-10.1007/s00701-014-2299-y Gamma Knife radiosurgery for low-grade tectal gliomas [Elektronische Daten] [Amr El-Shehaby, Wael Reda, Khaled Abdel Karim, Reem Emad Eldin, Ignatius Esene] Background: Tectal gliomas are present in a critical location that makes their surgical treatment difficult. Stereotactic radiosurgery presents an attractive noninvasive treatment option. However, tectal gliomas are also commonly associated with aqueductal obstruction and consequently hydrocephalus. This necessitates some form of CSF diversion procedure before radiosurgery. The aim of the study was to assess the efficacy and safety of Gamma Knife radiosurgery for tectal gliomas. Patients and methods: Between October 2002 and May 2011, 11 patients with tectal gliomas were treated with Gamma Knife radiosurgery. Five patients had pilocytic astrocytomas and six nonpilocytic astrocytomas. Ten patients presented with hydrocephalus and underwent a CSF diversion procedure [7V-P shunt and 3 endoscopic third ventriculostomy (ETV)]. The tumor volume ranged between 1.2-14.7cc (median 4.5cc). The prescription dose was 11-14Gy (median 12Gy). Results: Patients were followed for a median of 40months (13-114 months). Tumor control after radiosurgery was seen in all cases. In 6/11 cases, the tumors eventually disappeared after treatment. Peritumoral edema developed in 5/11 cases at an onset of 3-6 months after treatment. Transient tumor swelling was observed in four cases. Four patients developed cysts after treatment. One of these cases required aspiration and eventually disappeared, one became smaller spontaneously, and two remained stable. Conclusion: Gamma Knife radiosurgery is an effective and safe technique for treatment of tectal gliomas. Tumor shrinkage or disappearance after Gamma Knife radiosurgery may preclude the need for a shunt later on. Springer-Verlag Wien, 2014 Gamma Knife nationallicence Radiosurgery nationallicence Tectal nationallicence Glioma nationallicence Low grade nationallicence El-Shehaby Amr Gamma Knife Center Cairo, Cairo, Egypt aut Reda Wael Gamma Knife Center Cairo, Cairo, Egypt aut Abdel Karim Khaled Gamma Knife Center Cairo, Cairo, Egypt aut Emad Eldin Reem Gamma Knife Center Cairo, Cairo, Egypt aut Esene Ignatius Gamma Knife Center Cairo, Cairo, Egypt aut Acta Neurochirurgica Springer Vienna 157/2(2015-02-01), 247-256 0001-6268 157:2<247 2015 157 701 https://doi.org/10.1007/s00701-014-2299-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-014-2299-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- El-Shehaby Amr Gamma Knife Center Cairo, Cairo, Egypt aut NATIONALLICENCE 700 1- Reda Wael Gamma Knife Center Cairo, Cairo, Egypt aut NATIONALLICENCE 700 1- Abdel Karim Khaled Gamma Knife Center Cairo, Cairo, Egypt aut NATIONALLICENCE 700 1- Emad Eldin Reem Gamma Knife Center Cairo, Cairo, Egypt aut NATIONALLICENCE 700 1- Esene Ignatius Gamma Knife Center Cairo, Cairo, Egypt aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/2(2015-02-01), 247-256 0001-6268 157:2<247 2015 157 701