caa a22 4500 60621657X CHVBK 20210128101104.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s00701-014-2306-3 doi (NATIONALLICENCE)springer-10.1007/s00701-014-2306-3 Long-term follow-up of incidentally discovered meningiomas [Elektronische Daten] [Kayvan Jadid, Maria Feychting, Jonas Höijer, Sofia Hylin, Lars Kihlström, Tiit Mathiesen] Background: Many incidental meningiomas are detected and need to be assessed for further management. Better knowledge of the long-term natural history is necessary for optimal management. Methods: We have retrospectively evaluated a cohort of consecutive patients who were referred to the authors at the Department of Neurosurgery with incidentally diagnosed asymptomatic meningiomas from 1991-1998 and followed prospectively. All patients were followed for a minimum of 10years or until they reached the endpoint of demonstrated tumour growth or died. Results: During follow-up, 35.4% of the tumours grew, resulting in a 75% 15-year growth rate by life-table statistics. The growth rates were similar in smaller (<2cm) and larger tumours, while calcified tumours grew at a lower rate. The latter difference was, however, not statistically significant. Conclusion: Long-term tumour growth of incidentally detected asymptomatic meningiomas appeared to be much higher than expected. This information needs to be considered when discussing surgery, since the indication for surgery may be stronger than previously stated, especially for younger patients with tumours that can be reached at low risk. Springer-Verlag Wien, 2014 Meningioma nationallicence Incidental nationallicence Natural history nationallicence Jadid Kayvan Department of Neurosurgery, Karolinska University Hospital, 171 76, Stockholm, Sweden aut Feychting Maria Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden aut Höijer Jonas Unit of Biostatistics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden aut Hylin Sofia Department of Neurology, Karolinska University Hospital, 171 76, Stockholm, Sweden aut Kihlström Lars Department of Neurosurgery, Karolinska University Hospital, 171 76, Stockholm, Sweden aut Mathiesen Tiit Department of Neurosurgery, Karolinska University Hospital, 171 76, Stockholm, Sweden aut Acta Neurochirurgica Springer Vienna 157/2(2015-02-01), 225-230 0001-6268 157:2<225 2015 157 701 https://doi.org/10.1007/s00701-014-2306-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-014-2306-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Jadid Kayvan Department of Neurosurgery, Karolinska University Hospital, 171 76, Stockholm, Sweden aut NATIONALLICENCE 700 1- Feychting Maria Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden aut NATIONALLICENCE 700 1- Höijer Jonas Unit of Biostatistics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden aut NATIONALLICENCE 700 1- Hylin Sofia Department of Neurology, Karolinska University Hospital, 171 76, Stockholm, Sweden aut NATIONALLICENCE 700 1- Kihlström Lars Department of Neurosurgery, Karolinska University Hospital, 171 76, Stockholm, Sweden aut NATIONALLICENCE 700 1- Mathiesen Tiit Department of Neurosurgery, Karolinska University Hospital, 171 76, Stockholm, Sweden aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/2(2015-02-01), 225-230 0001-6268 157:2<225 2015 157 701