caa a22 4500 606216588 CHVBK 20210128101104.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s00701-014-2264-9 doi (NATIONALLICENCE)springer-10.1007/s00701-014-2264-9 True aqueductal tumors: a unique entity [Elektronische Daten] [Jonathan Roth, Kaisorn Chaichana, George Jallo, Giuseppe Mirone, Giuseppe Cinalli, Shlomi Constantini] Background: Pure aqueductal tumors (ATs) differ from pineal region and tectal/tegmental tumors in that they are epicentered within the aqueduct. Nevertheless, these tumors are rarely described as a separate type of tumor, and are often grouped with other lesions located in the same vicinity. The present multicenter study focuses on our experience treating patients with pure ATs. Methods: Data from three large tertiary centers was collected retrospectively, including presenting symptoms, treatment paradigm, surgical approaches, pathology, and outcome. Results: Between 1999 and 2013, 16 patients with AT were diagnosed and treated at the three tertiary centers. Ages at presentation ranged from 5.5 to 57years. Thirteen patients presented with hydrocephalus-related symptoms, and two were identified incidentally. Thirteen patients underwent an endoscopic third ventriculostomy, and two of these underwent a simultaneous endoscopic biopsy (one grade II ependymoma, one non-specified low-grade glioma). Two others underwent shunt placement. Three patients underwent resection due to tumor progression. Pathologies included glioblastoma multiforme, glioneural tumor, and ependymoma grade II. All non-resected tumors remained stable or grew only minimally. Conclusions: ATs are a rare entities that usually present with obstructive hydrocephalus. Treatment includes primarily cerebrospinal fluid drainage (preferably via an endoscopic third ventriculostomy). Simultaneous endoscopic biopsy may be done in selected cases. Tumor resection should be reserved for growing tumors; the trans-fourth ventricular or trans-choroidal approaches are probably safer than other approaches used to reach the tectal region. Springer-Verlag Wien, 2014 Aqueduct nationallicence Tumor nationallicence Hydrocephalus nationallicence Endoscopic third ventriculostomy nationallicence Endoscopic biopsy nationallicence Roth Jonathan Department of Pediatric Neurosurgery, Dana Children's Hospital, Tel-Aviv Medical Center, Tel-Aviv University, 6 Weizman Street, 64239, Tel Aviv, Israel aut Chaichana Kaisorn Department of Pediatric Neurosurgery, Johns Hopkins Children's Center, Baltimore, MD, USA aut Jallo George Department of Pediatric Neurosurgery, Johns Hopkins Children's Center, Baltimore, MD, USA aut Mirone Giuseppe Department of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, Naples, Italy aut Cinalli Giuseppe Department of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, Naples, Italy aut Constantini Shlomi Department of Pediatric Neurosurgery, Dana Children's Hospital, Tel-Aviv Medical Center, Tel-Aviv University, 6 Weizman Street, 64239, Tel Aviv, Israel aut Acta Neurochirurgica Springer Vienna 157/2(2015-02-01), 169-177 0001-6268 157:2<169 2015 157 701 https://doi.org/10.1007/s00701-014-2264-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-014-2264-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Roth Jonathan Department of Pediatric Neurosurgery, Dana Children's Hospital, Tel-Aviv Medical Center, Tel-Aviv University, 6 Weizman Street, 64239, Tel Aviv, Israel aut NATIONALLICENCE 700 1- Chaichana Kaisorn Department of Pediatric Neurosurgery, Johns Hopkins Children's Center, Baltimore, MD, USA aut NATIONALLICENCE 700 1- Jallo George Department of Pediatric Neurosurgery, Johns Hopkins Children's Center, Baltimore, MD, USA aut NATIONALLICENCE 700 1- Mirone Giuseppe Department of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, Naples, Italy aut NATIONALLICENCE 700 1- Cinalli Giuseppe Department of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, Naples, Italy aut NATIONALLICENCE 700 1- Constantini Shlomi Department of Pediatric Neurosurgery, Dana Children's Hospital, Tel-Aviv Medical Center, Tel-Aviv University, 6 Weizman Street, 64239, Tel Aviv, Israel aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/2(2015-02-01), 169-177 0001-6268 157:2<169 2015 157 701